NSC-144303
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MedKoo CAT#: 527785

CAS#: 108477-18-5

Description: NSC-144303 is a potent inhibitor of general DUB activity leading to acute proteotoxicstress and apoptosis.


Price and Availability

Size Price Shipping out time Quantity
10mg USD 360 2 Weeks
50mg USD 1205 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-08-03. Prices are subject to change without notice.

NSC-144303, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 527785
Name: NSC-144303
CAS#: 108477-18-5
Chemical Formula: C19H14N2O7S
Exact Mass: 414.0522
Molecular Weight: 414.388
Elemental Analysis: C, 55.07; H, 3.41; N, 6.76; O, 27.03; S, 7.74


Synonym: NSC-144303; NSC144303; NSC 144303; G5

IUPAC/Chemical Name: Tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-4H-thiopyran-4-one 1,1-dioxide

InChi Key: SSAMIOWVUGBIJK-KAVGSWPWSA-N

InChi Code: InChI=1S/C19H14N2O7S/c22-19-15(9-13-1-5-17(6-2-13)20(23)24)11-29(27,28)12-16(19)10-14-3-7-18(8-4-14)21(25)26/h1-10H,11-12H2/b15-9+,16-10+

SMILES Code: O=C(/C(C1)=C/C2=CC=C([N+]([O-])=O)C=C2)/C(CS1(=O)=O)=C/C3=CC=C([N+]([O-])=O)C=C3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Aleo E, Henderson CJ, Fontanini A, Solazzo B, Brancolini C. Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis. Cancer Res. 2006 Sep 15;66(18):9235-44. PubMed PMID: 16982768.