Cajucarinolide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584366

CAS#: 147742-03-8

Description: Cajucarinolide is a clerodane diterpene isolated from the cortices of Croton cajucara (Euphorbiaceae). This compound possesses anti-inflammatory activity and inhibits bee venom phospholipase A2 in vitro.


Chemical Structure

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Cajucarinolide
CAS# 147742-03-8

Theoretical Analysis

MedKoo Cat#: 584366
Name: Cajucarinolide
CAS#: 147742-03-8
Chemical Formula: C19H22O6
Exact Mass: 346.1416
Molecular Weight: 346.379
Elemental Analysis: C, 65.88; H, 6.40; O, 27.71

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Cajucarinolide

IUPAC/Chemical Name: Spiro(furan-3(2H),1'(7'H)-naphthalene)-2,7'-dione, 5-(2,5-dihydro-5-hydroxy-2-oxo-3-furanyl)-2',3',4,4',4'a,5,8',8'a-octahydro-2',5'-dimethyl-

InChi Key: KDHLKFOOPWLPCD-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H22O6/c1-9-5-11(20)6-14-12(9)4-3-10(2)19(14)8-15(24-18(19)23)13-7-16(21)25-17(13)22/h5,7,10,12,14-16,21H,3-4,6,8H2,1-2H3

SMILES Code: O=C1OC(C2=CC(O)OC2=O)CC13C(C)CCC4C(C)=CC(CC43)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 346.379 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Ichihara Y, Takeya K, Hitotsuyanagi Y, Morita H, Okuyama S, Suganuma M, Fujiki H, Motidome M, Itokawa H. Cajucarinolide and isocajucarinolide: anti-inflammatory diterpenes from Croton cajucara. Planta Med. 1992 Dec;58(6):549-51. PubMed PMID: 1484896.

2: Maciel MA, Pinto AC, Arruda AC, Pamplona SG, Vanderlinde FA, Lapa AJ, Echevarria A, Grynberg NF, Côlus IM, Farias RA, Luna Costa AM, Rao VS. Ethnopharmacology, phytochemistry and pharmacology: a successful combination in the study of Croton cajucara. J Ethnopharmacol. 2000 Apr;70(1):41-55. PubMed PMID: 10720788.