WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584357

CAS#: 101506-83-6

Description: Namirotene is a synthetic retinoic acid analog seen to be effective in the treatment of keratoconjunctivitis sicca (KCS) in rabbit.

Chemical Structure

CAS# 101506-83-6

Theoretical Analysis

MedKoo Cat#: 584357
Name: Namirotene
CAS#: 101506-83-6
Chemical Formula: C17H18O2S
Exact Mass: 286.10
Molecular Weight: 286.389
Elemental Analysis: C, 71.30; H, 6.34; O, 11.17; S, 11.19

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Namirotene; CBS 211A; Cbs 211 A

IUPAC/Chemical Name: Benzoic acid, 4-(2-(5-(1-methylethyl)-2-thienyl)-1-propenyl)-, (E)-


InChi Code: InChI=1S/C17H18O2S/c1-11(2)15-8-9-16(20-15)12(3)10-13-4-6-14(7-5-13)17(18)19/h4-11H,1-3H3,(H,18,19)/b12-10+

SMILES Code: O=C(O)C1=CC=C(/C=C(C2=CC=C(C(C)C)S2)\C)C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 286.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Taimi M, Defacque H, Commes T, Favero J, Dornand J, Marti J. The retinoic acid analog CBS-211A potentiates the 1 alpha,25-dihydroxyvitamin D3-induced differentiation of U937 cells. Agents Actions. 1993 Jan;38(1-2):91-9. PubMed PMID: 8480542.

2: Driot JY, Bonne C. Beneficial effects of a retinoic acid analog, CBS-211 A, on an experimental model of keratoconjunctivitis sicca. Invest Ophthalmol Vis Sci. 1992 Jan;33(1):190-5. PubMed PMID: 1730541.

3: Roussillon S, Bonne C, Coquelet C, Tournoux A. Quantitative parameters of a high-affinity binding site for retinoic acid in corneal endothelial cells. Cornea. 1986;5(3):145-9. PubMed PMID: 2980830.

4: Bonne C, Junquero D, Driot JY, Coquelet C, Modat G. [Effect of retinoids on the growth of corneal endothelial cells in culture]. Ophtalmologie. 1990 Jan-Feb;4(1):84-7. French. PubMed PMID: 2250947.

5: Junquéro D, Modat G, Coquelet C, Bonne C. Retinoid-induced potentiation of epidermal growth factor mitogenic effect on corneal endothelial cells. Cornea. 1990 Jan;9(1):41-4. PubMed PMID: 2297993.

6: Junquéro D, Modat G, Coquelet C, Bonne C. Retinoids enhance the number of EGF receptors in corneal endothelial cells. Exp Eye Res. 1990 Jul;51(1):49-53. PubMed PMID: 2373180.