Netzahualcoyone

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581111

CAS#: 87686-36-0

Description: Netzahualcoyone, the activity of netzahualcoyone on Bacillus subtilis and Escherichia coli was studied. The product inhibited the respiration of intact cells of B. subtilis but had no effect on the respiration of E. coli. However, when preparations of sonically disrupted cells were examined, inhibitory activity on both bacteria was observed.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-31. Prices are subject to change without notice.

Netzahualcoyone is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 581111
Name: Netzahualcoyone
CAS#: 87686-36-0
Chemical Formula: C30H36O6
Exact Mass: 492.2512
Molecular Weight: 492.61
Elemental Analysis: C, 73.15; H, 7.37; O, 19.49


Synonym: Netzahualcoyone;

IUPAC/Chemical Name: methyl (2R,3S,4aR,12bR,14aR,14bR)-3,10-dihydroxy-2,4a,6,9,12b,14a-hexamethyl-4,11-dioxo-1,2,3,4,4a,5,11,12b,13,14,14a,14b-dodecahydropicene-2-carboxylate

InChi Key: JBKXDADFFNVBTG-NUCARWLASA-N

InChi Code: InChI=1S/C30H36O6/c1-15-13-29(5)21(14-30(6,26(35)36-7)25(34)24(29)33)28(4)11-10-27(3)18(22(15)28)9-8-17-16(2)23(32)20(31)12-19(17)27/h8-9,12,21,25,32,34H,10-11,13-14H2,1-7H3/t21-,25-,27+,28-,29-,30-/m1/s1

SMILES Code: C1(C(=C(C2=CC=C3[C@@](CC[C@@]4(C)C3=C(C)C[C@@]3([C@@H]4C[C@@]([C@@H](C3=O)O)(C)C(=O)OC)C)(C)C2=C1)C)O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Moujir L, Gutiérrez-Navarro AM, González AG, Ravelo AG, Luis JG. Mode of action of netzahualcoyone. Antimicrob Agents Chemother. 1991 Jan;35(1):211-3. PubMed PMID: 1901699; PubMed Central PMCID: PMC244973.

2: Jeller AH, Silva DH, Lião LM, Bolzani Vda S, Furlan M. Antioxidant phenolic and quinonemethide triterpenes from Cheiloclinium cognatum. Phytochemistry. 2004 Jul;65(13):1977-82. PubMed PMID: 15280004.