YC 170

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341128

CAS#: 59946-73-5

Description: YC 170 is a biochemical.

Chemical Structure

YC 170
CAS# 59946-73-5

Theoretical Analysis

MedKoo Cat#: 341128
Name: YC 170
CAS#: 59946-73-5
Chemical Formula: C28H26ClN3O3
Exact Mass: 487.1663
Molecular Weight: 487.984
Elemental Analysis: C, 68.92; H, 5.37; Cl, 7.26; N, 8.61; O, 9.84

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: YC 170; YC-170; YC170

IUPAC/Chemical Name: 3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-1,4-dihydro-2,6-dimethyl-5-((phenylamino)carbonyl)-, 2-(2-pyridinyl)ethyl ester


InChi Code: InChI=1S/C28H26ClN3O3/c1-18-24(27(33)32-21-11-4-3-5-12-21)26(22-13-6-7-14-23(22)29)25(19(2)31-18)28(34)35-17-15-20-10-8-9-16-30-20/h3-14,16,26,31H,15,17H2,1-2H3,(H,32,33)

SMILES Code: CC1=C(C(C(=C(N1)C)C(=O)OCCc2ccccn2)c3ccccc3Cl)C(=O)Nc4ccccc4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 487.984 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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15: Kidooka M, Matsuda M, Handa J. Effect of calcium antagonist and agonist on free fatty acid liberation in the ischemic brain of rats. Surg Neurol. 1987 Jul;28(1):41-5. PubMed PMID: 2438789.

16: Nakaya H, Hattori Y, Tohse N, Kanno M. Voltage-dependent effects of YC-170, a dihydropyridine calcium channel modulator, in cardiovascular tissues. Naunyn Schmiedebergs Arch Pharmacol. 1986 Aug;333(4):421-30. PubMed PMID: 2430192.

17: Hattori Y, Nakaya H, Tohse N, Kanno M. Vascular and cardiac effects of a new dihydropyridine derivative, YC-170: a comparison with Bay K 8644. J Pharmacol Exp Ther. 1986 Aug;238(2):670-8. PubMed PMID: 2426442.

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20: Rogg H, Criscione L, Truog A, Meier M. In vitro comparative studies of the calcium-entry activators YC-170, CGP 28392, and BAY K 8644. J Cardiovasc Pharmacol. 1985;7 Suppl 6:S31-7. PubMed PMID: 2414592.