Yanangin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341116

CAS#: 105705-86-0

Description: Yanangin


Chemical Structure

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Yanangin
CAS# 105705-86-0

Theoretical Analysis

MedKoo Cat#: 341116
Name: Yanangin
CAS#: 105705-86-0
Chemical Formula: C36H36N2O6
Exact Mass: 592.2573
Molecular Weight: 592.692
Elemental Analysis: C, 72.95; H, 6.12; N, 4.73; O, 16.20

Size Price Shipping out time Quantity
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Pricing updated 2021-03-05. Prices are subject to change without notice.

Yanangin is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Synonym: Yanangin; Yanangine.

IUPAC/Chemical Name: 26,46-dimethoxy-42,411-dimethyl-41,42,43,44,49,410,411,412-octahydro-4(1,12)-[1,4]dioxino[2,3-g:6,5-h']diisoquinolina-1,2(1,3)-dibenzenacyclopentaphane-16,45-diol

InChi Key: SKVLZQWBNXMJEZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C36H36N2O6/c1-37-11-9-21-17-30-31-18-23(21)26(37)15-19-5-7-28(39)24(13-19)25-14-20(6-8-29(25)41-3)16-27-32-22(10-12-38(27)2)33(40)35(42-4)36(44-30)34(32)43-31/h5-8,13-14,17-18,26-27,39-40H,9-12,15-16H2,1-4H3

SMILES Code: CN(CC1)C(C2)C(C1=C3)=CC4=C3OC5=C(OC)C(O)=C(CCN(C)C6CC7=CC(C8=CC2=CC=C8O)=C(OC)C=C7)C6=C5O4

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Handling Instructions:

Preparing Stock Solutions

The following data is based on the product molecular weight 592.692 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Koga R, Kubota M, Hashiguchi T, Yanagi Y, Ohno S. Annexin A2 Mediates the Localization of Measles Virus Matrix Protein at the Plasma Membrane. J Virol. 2018 Feb 28. pii: JVI.00181-18. doi: 10.1128/JVI.00181-18. [Epub ahead of print] PubMed PMID: 29491166.

2: Nishimura T, Yamashita K, Takahashi S, Yamao T, Hotta S, Yanagi H, Nakayama M. Quantitative evaluation of light-matter interaction parameters in organic single-crystal microcavities. Opt Lett. 2018 Mar 1;43(5):1047-1050. doi: 10.1364/OL.43.001047. PubMed PMID: 29489777.

3: Hashiguchi T, Fukuda Y, Matsuoka R, Kuroda D, Kubota M, Shirogane Y, Watanabe S, Tsumoto K, Kohda D, Plemper RK, Yanagi Y. Structures of the prefusion form of measles virus fusion protein in complex with inhibitors. Proc Natl Acad Sci U S A. 2018 Feb 20. pii: 201718957. doi: 10.1073/pnas.1718957115. [Epub ahead of print] PubMed PMID: 29463726.

4: Iijima T, Niitani T, Tanaka S, Yanagi K, Jojima T, Suzuki K, Usui I, Aso Y. Concurrent variant type 3 autoimmune polyglandular syndrome and pulmonary arterial hypertension in a Japanese woman. Endocr J. 2018 Feb 16. doi: 10.1507/endocrj.EJ17-0465. [Epub ahead of print] PubMed PMID: 29459556.

5: Bamgbose BO, Sato A, Yanagi Y, Hisatomi M, Takeshita Y, Sugianto I, Asaumi J. A Case of Schwannoma of the Submandibular Region. Open Dent J. 2018 Jan 29;12:12-18. doi: 10.2174/1874210601812010012. eCollection 2018. PubMed PMID: 29456769; PubMed Central PMCID: PMC5806283.

6: Matsubara R, Yanagi Y, Oki K, Hisatomi M, Santos KC, Bamgbose BO, Fujita M, Okada S, Minagi S, Asaumi J. Assessment of MRI findings and clinical symptoms in patients with temporomandibular joint disorders. Dentomaxillofac Radiol. 2018 Feb 22:20170412. doi: 10.1259/dmfr.20170412. [Epub ahead of print] PubMed PMID: 29451403.

7: Hori M, Guo JD, Yanagi T, Nogi K, Sasamori T, Yorimitsu H. Synthesis of Biaryls via Hypervalent Iodine-Tethered Sigmatropic Rearrangement. Angew Chem Int Ed Engl. 2018 Feb 16. doi: 10.1002/anie.201801132. [Epub ahead of print] PubMed PMID: 29451348.

8: Chinen Y, Nakamura S, Ganaha A, Hayashi S, Inazawa J, Yanagi K, Nakanishi K, Kaname T, Naritomi K. Mild prominence of the Sylvian fissure in a Bainbridge-Ropers syndrome patient with a novel frameshift variant in ASXL3. Clin Case Rep. 2017 Dec 28;6(2):330-336. doi: 10.1002/ccr3.1361. eCollection 2018 Feb. PubMed PMID: 29445472; PubMed Central PMCID: PMC5799615.

9: Miyazono S, Hasegawa K, Miyazaki S, Sakakima H, Konno S, Meguro S, Sasajima H, Noguchi T, Osada K, Kashiwayanagi M. Etizolam attenuates the reduction in cutaneous temperature induced in mice by exposure to synthetic predator odor. Eur J Pharmacol. 2018 Apr 5;824:157-162. doi: 10.1016/j.ejphar.2018.02.015. Epub 2018 Feb 10. PubMed PMID: 29438703.

10: Takagi A, Ozawa H, Oki M, Yanagi H, Nabeshima K, Nakamura N. A Case of Helicobacter pylori-negative Advanced Gastric Cancer with Massive Eosinophilia. Intern Med. 2018 Feb 9. doi: 10.2169/internalmedicine.0013-17. [Epub ahead of print] PubMed PMID: 29434119.

11: Tohgasaki T, Ozawa N, Yoshino T, Ishiwatari S, Matsukuma S, Yanagi S, Fukuda H. Enolase-1 expression in the stratum corneum is elevated with parakeratosis of atopic dermatitis and disrupts the cellular tight junction barrier in keratinocytes. Int J Cosmet Sci. 2018 Feb 11. doi: 10.1111/ics.12449. [Epub ahead of print] PubMed PMID: 29430682.

12: Kitamura S, Yanagi T, Inamura-Takashima Y, Imafuku K, Hata H, Fujioka Y, Ohba Y, Shimizu H. Dermoscopic evaluation for skin grafts after surgery; neo-vascularization correlates with survival of skin grafts: A prospective study. J Dermatol Sci. 2018 Feb 2. pii: S0923-1811(18)30079-3. doi: 10.1016/j.jdermsci.2018.01.014. [Epub ahead of print] PubMed PMID: 29428816.

13: Ishikawa Y, Yanagi Y, Suzuki M, Konomi U. A questionnaire to assess olfactory rehabilitation for laryngectomized patients (Provox voice prosthesis users) in Japan. Auris Nasus Larynx. 2018 Feb 7. pii: S0385-8146(17)30907-0. doi: 10.1016/j.anl.2018.01.015. [Epub ahead of print] PubMed PMID: 29428493.

14: Takahashi Y, Matsuura T, Yoshimaru K, Yanagi Y, Hayashida M, Taguchi T. Liver graft-to-spleen volume ratio as a useful predictive factor of the early graft function in children and young adults transplanted for biliary atresia: a retrospective study. Transpl Int. 2018 Feb 9. doi: 10.1111/tri.13131. [Epub ahead of print] PubMed PMID: 29424478.

15: Yanagi M, Suzuki A, Hudson RHE, Saito Y. A fluorescent 3,7-bis-(naphthalen-1-ylethynylated)-2'-deoxyadenosine analogue reports thymidine in complementary DNA by a large emission Stokes shift. Org Biomol Chem. 2018 Feb 28;16(9):1496-1507. doi: 10.1039/c8ob00062j. PubMed PMID: 29417128.

16: Ono H, Saitsu H, Horikawa R, Nakashima S, Ohkubo Y, Yanagi K, Nakabayashi K, Fukami M, Fujisawa Y, Ogata T. Partial androgen insensitivity syndrome caused by a deep intronic mutation creating an alternative splice acceptor site of the AR gene. Sci Rep. 2018 Feb 2;8(1):2287. doi: 10.1038/s41598-018-20691-9. PubMed PMID: 29396419; PubMed Central PMCID: PMC5797100.

17: Yanagi A, Sumita Y, Hattori M, Kamiyanagi A, Otomaru T, Kanazaki A, Haraguchi M, Murase M, Hatano N, Taniguchi H. Clinical survey over the past 35 years at the clinic for maxillofacial prosthetics Tokyo Medical and Dental University. J Prosthodont Res. 2018 Jan 29. pii: S1883-1958(17)30133-0. doi: 10.1016/j.jpor.2017.12.002. [Epub ahead of print] PubMed PMID: 29396268.

18: Sugianto I, Yanagi Y, Konouchi H, Hisatomi M, Okada S, Bamgbose BO, Asaumi J. Incidental finding of papillary thyroid carcinoma on CT examination of mandibular lesion: Case report. Mol Clin Oncol. 2018 Jan;8(1):183-187. doi: 10.3892/mco.2017.1478. Epub 2017 Nov 2. PubMed PMID: 29387413; PubMed Central PMCID: PMC5768132.

19: Kitamura S, Yanagi T, Inamura-Takashima Y, Imafuku K, Hata H, Uehara J, Ishida Y, Otsuka A, Hirata K, Shimizu H. Retrospective study on the correlation between 18-fluorodeoxyglucose uptake in positron emission tomography-computer tomography and tumour volume, cytological activity as assessed with Ki-67 and GLUT-1 staining in 10 cases of Merkel cell carcinoma. J Eur Acad Dermatol Venereol. 2018 Jan 29. doi: 10.1111/jdv.14821. [Epub ahead of print] PubMed PMID: 29377285.

20: Yanagi M, Sasaki K, Uchikado Y, Omoto I, Arigami T, Kurahara H, Uenosono Y, Sakoda M, Maemura K, Natsugoe S. Effect of Neoadjuvant Chemoradiotherapy on Lymph Node Micrometastases in Thoracic Esophageal Cancer. Anticancer Res. 2018 Feb;38(2):893-900. PubMed PMID: 29374717.