UBP618

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MedKoo CAT#: 555173

CAS#: 1333110-86-3

Description: UBP618 is a pan-inhibitor of GluN1/GluN2 receptors.


Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-10-29. Prices are subject to change without notice.

UBP618 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555173
Name: UBP618
CAS#: 1333110-86-3
Chemical Formula: C17H11BrO3
Exact Mass: 341.9892
Molecular Weight: 343.176
Elemental Analysis: C, 59.50; H, 3.23; Br, 23.28; O, 13.99


Synonym: UBP618; UBP-618; UBP 618.

IUPAC/Chemical Name: 4-Bromo-3-hydroxy-7-phenyl-naphthalene-2-carboxylic acid

InChi Key: UISPFOJJZIPYLC-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H11BrO3/c18-15-13-7-6-11(10-4-2-1-3-5-10)8-12(13)9-14(16(15)19)17(20)21/h1-9,19H,(H,20,21)

SMILES Code: O=C(C1=C(O)C(Br)=C2C=CC(C3=CC=CC=C3)=CC2=C1)O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Monaghan DT, Irvine MW, Costa BM, Fang G, Jane DE. Pharmacological modulation
of NMDA receptor activity and the advent of negative and positive allosteric
modulators. Neurochem Int. 2012 Sep;61(4):581-92. doi:
10.1016/j.neuint.2012.01.004. Epub 2012 Jan 17. Review. PubMed PMID: 22269804;
PubMed Central PMCID: PMC3360989.

2: Costa BM, Irvine MW, Fang G, Eaves RJ, Mayo-Martin MB, Laube B, Jane DE,
Monaghan DT. Structure-activity relationships for allosteric NMDA receptor
inhibitors based on 2-naphthoic acid. Neuropharmacology. 2012 Mar;62(4):1730-6.
doi: 10.1016/j.neuropharm.2011.11.019. Epub 2011 Dec 6. PubMed PMID: 22155206;
PubMed Central PMCID: PMC3269548.