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MedKoo CAT#: 555172

CAS#: 1357838-47-1

Description: UBP684 is a NMDAR pan-PAM (positive allosteric modulator) which robustly potentiates responses at all GluN1/GluN2 subtypes and at neuronal NMDARs. UBP684 increases the maximal l-glutamate/glycine response while having minor subunit-specific effects on agonist potency.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-30. Prices are subject to change without notice.

UBP684 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 555172
Name: UBP684
CAS#: 1357838-47-1
Chemical Formula: C17H20O2
Exact Mass: 256.1463
Molecular Weight: 256.345
Elemental Analysis: C, 79.65; H, 7.86; O, 12.48

Synonym: UBP684; UBP-684; UBP 684;

IUPAC/Chemical Name: 6-(4-methylpentyl)naphthalene-2-carboxylic acid


InChi Code: InChI=1S/C17H20O2/c1-12(2)4-3-5-13-6-7-15-11-16(17(18)19)9-8-14(15)10-13/h6-12H,3-5H2,1-2H3,(H,18,19)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Chopra DA, Sapkota K, Irvine MW, Fang G, Jane DE, Monaghan DT, Dravid SM. A
single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA
receptors. Sci Rep. 2017 Jul 31;7(1):6933. doi: 10.1038/s41598-017-07292-8.
PubMed PMID: 28761055; PubMed Central PMCID: PMC5537304.

2: Sapkota K, Irvine MW, Fang G, Burnell ES, Bannister N, Volianskis A, Culley
GR, Dravid SM, Collingridge GL, Jane DE, Monaghan DT. Mechanism and properties of
positive allosteric modulation of N-methyl-d-aspartate receptors by 6-alkyl
2-naphthoic acid derivatives. Neuropharmacology. 2017 Oct;125:64-79. doi:
10.1016/j.neuropharm.2017.07.007. Epub 2017 Jul 11. PubMed PMID: 28709671; PubMed
Central PMCID: PMC5623084.