Carbofuran
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341101

CAS#: 1563-66-2

Description: Carbofuran is one of the most toxic carbamate pesticides.


Chemical Structure

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Carbofuran
CAS# 1563-66-2

Theoretical Analysis

MedKoo Cat#: 341101
Name: Carbofuran
CAS#: 1563-66-2
Chemical Formula: C12H15NO3
Exact Mass: 221.1052
Molecular Weight: 221.256
Elemental Analysis: C, 65.14; H, 6.83; N, 6.33; O, 21.69

Price and Availability

Size Price Availability Quantity
250.0mg USD 180.0 2 Weeks
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Synonym: Carbofuran; D 1221; D-1221; D1221; Furadan.

IUPAC/Chemical Name: 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, 7-(N-methylcarbamate)

InChi Key: DUEPRVBVGDRKAG-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)

SMILES Code: c12c(CC(O2)(C)C)cccc1OC(NC)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 221.256 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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5: Alves AAA, Ruiz GLO, Nonato TCM, Müller LC, Sens ML. Performance of the fixed-bed of granular activated carbon for the removal of pesticides from water supply. Environ Technol. 2018 Feb 26:1-11. doi: 10.1080/09593330.2018.1435731. [Epub ahead of print] PubMed PMID: 29383989.

6: Berton A, Brugnera MF, Dores EFGC. Grab and passive sampling applied to pesticide analysis in the São Lourenço river headwater in Campo Verde - MT, Brazil. J Environ Sci Health B. 2018 Apr 3;53(4):237-245. doi: 10.1080/03601234.2017.1410412. Epub 2018 Jan 16. PubMed PMID: 29336664.

7: Baumert BO, Carnes MU, Hoppin JA, Jackson CL, Sandler DP, Freeman LB, Henneberger PK, Umbach DM, Shrestha S, Long S, London SJ. Sleep apnea and pesticide exposure in a study of US farmers. Sleep Health. 2018 Feb;4(1):20-26. doi: 10.1016/j.sleh.2017.08.006. Epub 2017 Sep 28. PubMed PMID: 29332674; PubMed Central PMCID: PMC5771434.

8: Geng Y, Jiang L, Zhang Y, He Z, Wang L, Peng Y, Wang Y, Liu X, Xu Y. Dissipation, pre-harvest interval estimation, and dietary risk assessment of carbosulfan, dimethoate, and their relevant metabolites in greenhouse cucumber (Cucumis sativus L.). Pest Manag Sci. 2018 Jan 12. doi: 10.1002/ps.4857. [Epub ahead of print] PubMed PMID: 29327491.

9: Amatatongchai M, Sroysee W, Jarujamrus P, Nacapricha D, Lieberzeit PA. Selective amperometric flow-injection analysis of carbofuran using a molecularly-imprinted polymer and gold-coated-magnetite modified carbon nanotube-paste electrode. Talanta. 2018 Mar 1;179:700-709. doi: 10.1016/j.talanta.2017.11.064. Epub 2017 Dec 5. PubMed PMID: 29310297.

10: Eddy NO, Essien NB. Computational chemistry study of toxicity of some m-tolyl acetate derivatives insecticides and molecular design of structurally related products. In Silico Pharmacol. 2017 Nov 17;5(1):14. doi: 10.1007/s40203-017-0036-y. eCollection 2017. PubMed PMID: 29308350; PubMed Central PMCID: PMC5755710.

11: Wei JC, Wei B, Yang W, He CW, Su HX, Wan JB, Li P, Wang YT. Trace determination of carbamate pesticides in medicinal plants by a fluorescent technique. Food Chem Toxicol. 2017 Dec 18. pii: S0278-6915(17)30760-3. doi: 10.1016/j.fct.2017.12.019. [Epub ahead of print] PubMed PMID: 29269059.

12: Ha B, Zamini L, Monn J, Njoroge S, Thimo L, Ondeti M, Murungi JI, Muhoro CN. Tropical surface water quality studies: Implications for the aquatic fate of N-methyl carbamate pesticides. J Environ Sci Health B. 2018 Mar 4;53(3):161-170. doi: 10.1080/03601234.2017.1399768. Epub 2017 Dec 5. PubMed PMID: 29206083.

13: Ćwieląg-Piasecka I, Witwicki M, Jerzykiewicz M, Jezierska J. Can Carbamates Undergo Radical Oxidation in the Soil Environment? A Case Study on Carbaryl and Carbofuran. Environ Sci Technol. 2017 Dec 19;51(24):14124-14134. doi: 10.1021/acs.est.7b03386. Epub 2017 Dec 6. PubMed PMID: 29171253.

14: Lehmann E, Fargues M, Nfon Dibié JJ, Konaté Y, de Alencastro LF. Assessment of water resource contamination by pesticides in vegetable-producing areas in Burkina Faso. Environ Sci Pollut Res Int. 2018 Feb;25(4):3681-3694. doi: 10.1007/s11356-017-0665-z. Epub 2017 Nov 21. PubMed PMID: 29164468.

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19: Seth B, Yadav A, Agarwal S, Tiwari SK, Chaturvedi RK. Inhibition of the transforming growth factor-β/SMAD cascade mitigates the anti-neurogenic effects of the carbamate pesticide carbofuran. J Biol Chem. 2017 Nov 24;292(47):19423-19440. doi: 10.1074/jbc.M117.798074. Epub 2017 Oct 5. PubMed PMID: 28982980; PubMed Central PMCID: PMC5702680.

20: Jaiswal SK, Gupta VK, Siddiqi NJ, Sharma B. Curcumin mediated attenuation of carbofuran induced toxicity in the heart of Wistar rats. Cell Mol Biol (Noisy-le-grand). 2017 Jul 31;63(6):12-17. doi: 10.14715/cmb/2017.63.6.3. PubMed PMID: 28968202.

Carbofuran

250.0mg / USD 180.0