Y 25510

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341087

CAS#: 145194-32-7

Description: Y 25510 is a biochemical.

Chemical Structure

Y 25510
CAS# 145194-32-7

Theoretical Analysis

MedKoo Cat#: 341087
Name: Y 25510
CAS#: 145194-32-7
Chemical Formula: C19H22N4O3
Exact Mass: 354.1692
Molecular Weight: 354.41
Elemental Analysis: C, 64.39; H, 6.26; N, 15.81; O, 13.54

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Pricing updated 2021-03-05. Prices are subject to change without notice.

Y 25510 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Synonym: Y 25510; Y-25510; Y25510.

IUPAC/Chemical Name: 1H-Pyrazolo(3,4-b)pyridine-1-acetic acid, 3-(4-(2-(dimethylamino)-1-methylethoxy)phenyl)-, (+-)-


InChi Code: InChI=1S/C19H22N4O3/c1-13(11-22(2)3)26-15-8-6-14(7-9-15)18-16-5-4-10-20-19(16)23(21-18)12-17(24)25/h4-10,13H,11-12H2,1-3H3,(H,24,25)

SMILES Code: CC(CN(C)C)Oc1ccc(cc1)c2c3cccnc3n(n2)CC(=O)O

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Handling Instructions:

Preparing Stock Solutions

The following data is based on the product molecular weight 354.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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1: Azuma J, Ogura M, Yamamoto I, Hisadome M, Fukuda T, Ikeda Y, Mori H, Oka T, Asano S. The effect of Y-25510 injection on the serum levels of some cytokines in healthy adult volunteers. Eur J Clin Pharmacol. 1998 Feb;53(6):411-9. PubMed PMID: 9551699.

2: Kusuhara H, Komatsu H, Hisadome M, Ikeda Y. (+/-)-3-[4-(2-dimethylamino-1-methylethoxy)-phenyl]-1H-pyrazolo[3,4- B]pyridine-1-acetic acid (Y-25510) stimulates production of IL-1 beta and IL-6 at the level of messenger RNA expression in cultured human monocytes. Int J Immunopharmacol. 1996 Dec;18(12):719-28. PubMed PMID: 9172015.

3: Hisadome M, Fukuda T, Matsuyuki H, Ikeda Y, Nomoto K. Enhancement of in vivo production of IL-1 alpha and IL-6 in mice by Y-25510, a 1H-pyrazolo[3,4-b]pyridine-1 acetic acid derivative. Int J Immunopharmacol. 1996 Jun-Jul;18(6-7):379-84. PubMed PMID: 9024939.

4: Hisadome M, Fukuda T, Terasawa M, Oe T, Takahata H, Goto K, Tsuru S, Nomoto K. Enhancement of host defense by Y-25510, (+-)-3-[4-(2-dimethylamino-1-methylethoxy)phenyl]-1H-pyrazolo[3,4 -b] pyridine-1-acetic acid, a novel synthetic compound. A comparison with recombinant human granulocyte colony-stimulating factor in 5-fluorouracil-treated mice. Int J Immunopharmacol. 1992 Oct;14(7):1195-201. PubMed PMID: 1280628.