Y 27152
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341077

CAS#: 127408-30-4

Description: Y 27152 is a biochemical.


Chemical Structure

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Y 27152
CAS# 127408-30-4

Theoretical Analysis

MedKoo Cat#: 341077
Name: Y 27152
CAS#: 127408-30-4
Chemical Formula: C21H22N2O4
Exact Mass: 366.158
Molecular Weight: 366.417
Elemental Analysis: C, 68.84; H, 6.05; N, 7.65; O, 17.47

Size Price Shipping out time Quantity
10mg USD 425 2 Weeks
50mg USD 1205 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-03-05. Prices are subject to change without notice.

purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Synonym: Y 27152; Y-27152; Y27152.

IUPAC/Chemical Name: Acetamide, N-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)-N-(phenylmethoxy)-, (3S-trans)-

InChi Key: RHFUXPCCELGMFC-PMACEKPBSA-N

InChi Code: InChI=1S/C21H22N2O4/c1-14(24)23(26-13-15-7-5-4-6-8-15)19-17-11-16(12-22)9-10-18(17)27-21(2,3)20(19)25/h4-11,19-20,25H,13H2,1-3H3/t19-,20-/m0/s1

SMILES Code: C(C)(=O)N(OCc1ccccc1)[C@@H]1[C@@H](C(Oc2c1cc(cc2)C#N)(C)C)O

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Handling Instructions:

Preparing Stock Solutions

The following data is based on the product molecular weight 366.417 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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1: Uematsu T, Kosuge K, Hirosawa S, Kadobe Y, Hibi T, Nakashima M. Pharmacokinetics and safety of a novel, long-acting, prodrug-type potassium channel opener, Y-27152, in healthy volunteers. J Clin Pharmacol. 1996 May;36(5):439-51. PubMed PMID: 8739023.

2: Nakajima T, Shinohara T, Yaoka O, Fukunari A, Shinagawa K, Aoki K, Katoh A, Yamanaka T, Setoguchi M, Tahara T. Y-27152, a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state. J Pharmacol Exp Ther. 1992 May;261(2):730-6. PubMed PMID: 1578381.