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ALB-127158A
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555162

CAS#: 1173154-32-9

Description: ALB-127158A, also known as ALB-127158(a), is a MCH1 antagonist for the treatment of obesity. Preclinical studies demonstrated that the compound produced significant weight loss in rodents. ALB-127158(a) may be a potential treatment for IBD. This example demonstrates how using data from the preclinical studies is possible to build decision points into an early clinical development plan that will allow early assessment of potential efficacy and allow timely go/no go decisions.


Price and Availability

Size Price Shipping out time Quantity
100mg USD 1350 2 Weeks
200mg USD 1850 2 Weeks
500mg USD 2650 2 Weeks
1g USD 3850 2 Weeks
2g USD 5950 2 Weeks
5g USD 11650 2 Weeks
Inquire bulk and customized quantity
Pricing updated 2020-10-30. Prices are subject to change without notice.

ALB-127158A, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 555162
Name: ALB-127158A
CAS#: 1173154-32-9
Chemical Formula: C23H21FN4O2
Exact Mass: 404.1649
Molecular Weight: 404.4454
Elemental Analysis: C, 68.30; H, 5.23; F, 4.70; N, 13.85; O, 7.91


Synonym: ALB-127158A; ALB 127158A; ALB127158A; ALB-127158(a); ALB127158(a); ALB 127158(a); ALB-127158; ALB 127158; ALB127158;

IUPAC/Chemical Name: 2(1H)-Pyridinone, 4-[(5-fluoro-2-pyridinyl)methoxy]-1-(2,3,4,5-tetrahydro-5-methyl-1H-pyrido[4,3-b]indol-7-yl)-

InChi Key: VUUUHLIHQHVLLE-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H21FN4O2/c1-27-21-6-8-25-13-20(21)19-5-4-17(10-22(19)27)28-9-7-18(11-23(28)29)30-14-16-3-2-15(24)12-26-16/h2-5,7,9-12,25H,6,8,13-14H2,1H3

SMILES Code: O=C1C=C(OCC2=NC=C(F)C=C2)C=CN1C3=CC4=C(C=C3)C(CNCC5)=C5N4C


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Moore NA, Sargent BJ, Guzzo PR, Surman MD. From preclinical to clinical
development: the example of a novel treatment for obesity. Neurobiol Dis. 2014
Jan;61:47-54. doi: 10.1016/j.nbd.2013.07.009. Epub 2013 Jul 25. Review. PubMed
PMID: 23891728.