SB-429201

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562156

CAS#: 1027971-34-1

Description: SB-429201 is a potent, selective HDAC1 inhibitor.

Chemical Structure

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SB-429201
CAS# 1027971-34-1
Instruction

Theoretical Analysis

MedKoo Cat#: 562156
Name: SB-429201
CAS#: 1027971-34-1
Chemical Formula: C28H24N2O3
Exact Mass: 436.18
Molecular Weight: 436.510
Elemental Analysis: C, 77.04; H, 5.54; N, 6.42; O, 11.00

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: SB-429201; SB 429201; SB429201;

IUPAC/Chemical Name: N-(4-Phenoxyphenyl)-4-(3-phenylpropanamido)benzamide

InChi Key: YPXLCXVERGDWHW-UHFFFAOYSA-N

InChi Code: InChI=1S/C28H24N2O3/c31-27(20-11-21-7-3-1-4-8-21)29-23-14-12-22(13-15-23)28(32)30-24-16-18-26(19-17-24)33-25-9-5-2-6-10-25/h1-10,12-19H,11,20H2,(H,29,31)(H,30,32)

SMILES Code: O=C(NC1=CC=C(OC2=CC=CC=C2)C=C1)C3=CC=C(NC(CCC4=CC=CC=C4)=O)C=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 436.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Hu E, Dul E, Sung CM, Chen Z, Kirkpatrick R, Zhang GF, Johanson K, Liu R, Lago A, Hofmann G, Macarron R, de los Frailes M, Perez P, Krawiec J, Winkler J, Jaye M. Identification of novel isoform-selective inhibitors within class I histone deacetylases. J Pharmacol Exp Ther. 2003 Nov;307(2):720-8. Epub 2003 Sep 15. PubMed PMID: 12975486.