NU-7163

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562121

CAS#: 503468-03-9

Description: NU-7163 is a potent and selective, ATP-competitive DNA-PK inhibitor.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-08-08. Prices are subject to change without notice.

NU-7163 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 562121
Name: NU-7163
CAS#: 503468-03-9
Chemical Formula: C18H17NO3
Exact Mass: 295.1208
Molecular Weight: 295.33
Elemental Analysis: C, 73.20; H, 5.80; N, 4.74; O, 16.25


Synonym: NU-7163; NU 7163; NU7163;

IUPAC/Chemical Name: 2-(2-Methylmorpholin-4-yl)benzo[h]chromen-4-one

InChi Key: RFWCIJWQGHFULK-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H17NO3/c1-12-11-19(8-9-21-12)17-10-16(20)15-7-6-13-4-2-3-5-14(13)18(15)22-17/h2-7,10,12H,8-9,11H2,1H3

SMILES Code: O=C1C=C(N2CC(C)OCC2)OC3=C1C=CC4=CC=CC=C43


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Griffin RJ, Fontana G, Golding BT, Guiard S, Hardcastle IR, Leahy JJ, Martin N, Richardson C, Rigoreau L, Stockley M, Smith GC. Selective benzopyranone and pyrimido[2,1-a]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro. J Med Chem. 2005 Jan 27;48(2):569-85. PubMed PMID: 15658870.