WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 527682

CAS#: 37804-11-8

Description: ACDPP HCl is a mGluR5 inhibitor.

Chemical Structure

CAS# 37804-11-8

Theoretical Analysis

MedKoo Cat#: 527682
CAS#: 37804-11-8
Chemical Formula: C12H14Cl2N6O
Exact Mass: 328.0606
Molecular Weight: 329.185
Elemental Analysis: C, 43.78; H, 4.29; Cl, 21.54; N, 25.53; O, 4.86

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: ACDPP HCl

IUPAC/Chemical Name: 3-Amino-6-chloro-5-(dimethylamino)-N-(pyridin-3-yl)pyrazine-2-carboxamide Hydrochloride


InChi Code: InChI=1S/C12H13ClN6O.ClH/c1-19(2)11-9(13)17-8(10(14)18-11)12(20)16-7-4-3-5-15-6-7;/h3-6H,1-2H3,(H2,14,18)(H,16,20);1H

SMILES Code: O=C(C1=NC(Cl)=C(N(C)C)N=C1N)NC2=CC=CN=C2.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 329.185 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Bennett J, Doyle RJ, Lee HY, Lu D, Salem G, Speldewinde DJ, Tifan M, Willis AC. Synthesis of 1,3-azaphosphol-2-ones. Crystal and molecular structures of [SP-4-2]-dichlorobis(3-phenyl-1,3-dihydrobenzo[1,3]azaphosphol-2-one-P)palladium( II) and its chloro(methyl)platinum(II) analogue. Dalton Trans. 2010 Jan 7;(1):256-64. doi: 10.1039/b916913j. Epub 2009 Nov 10. PubMed PMID: 20023958.

2: White DR, Heavner SB, Hardy SM, Prazma J. Gastroesophageal reflux and eustachian tube dysfunction in an animal model. Laryngoscope. 2002 Jun;112(6):955-61. PubMed PMID: 12160291.

3: Jahanmard E, Suyama K. Bisphenol derivative of allysine for high-performance liquid chromatographic analysis of allysine residue of proteins. J Chromatogr B Biomed Sci Appl. 2000 Mar 10;739(2):273-80. PubMed PMID: 10755371.