WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 206858

CAS#: 1952236-05-3

Description: MTX-211 is a dual inhibitor of EGFR and PI3K. MTX-211 is potentially useful for treatment of KRAS mutant colorectal cancer.

Chemical Structure

CAS# 1952236-05-3

Theoretical Analysis

MedKoo Cat#: 206858
Name: MTX-211
CAS#: 1952236-05-3
Chemical Formula: C20H14Cl2FN5O2S
Exact Mass: 477.0229
Molecular Weight: 478.3234
Elemental Analysis: C, 50.22; H, 2.95; Cl, 14.82; F, 3.97; N, 14.64; O, 6.69; S, 6.70

Price and Availability

Size Price Availability Quantity
5.0mg USD 350.0 2 Weeks
10.0mg USD 600.0 2 Weeks
50.0mg USD 1650.0 2 Weeks
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Synonym: MTX-211; MTX211; MTX 211.

IUPAC/Chemical Name: N-[2-chloro-5-[4-(3-chloro-4-fluoroanilino)quinazolin-6-yl]pyridin-3-yl]methanesulfonamide


InChi Code: InChI=1S/C20H14Cl2FN5O2S/c1-31(29,30)28-18-7-12(9-24-19(18)22)11-2-5-17-14(6-11)20(26-10-25-17)27-13-3-4-16(23)15(21)8-13/h2-10,28H,1H3,(H,25,26,27)

SMILES Code: CS(=O)(NC1=CC(C2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2)=CN=C1Cl)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 478.3234 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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5.0mg / USD 350.0