WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555130

CAS#: 2172617-16-0

Description: YKL-06-062 is a second-generation SIK inhibitor. YKL 06-062 induces significant pigmentation after 8 days of treatment (1×/day). YKL 06-062 did not require mechanical application (rubbing) to induce significant human epidermal darkening. YKL-06-062 induces not only synthesis of melanin but also melanosomal maturation, export, and localization features, even after import into keratinocytes.

Chemical Structure

CAS# 2172617-16-0

Theoretical Analysis

MedKoo Cat#: 555130
Name: YKL-06-062
CAS#: 2172617-16-0
Chemical Formula: C31H39N7O
Exact Mass: 525.3216
Molecular Weight: 525.701
Elemental Analysis: C, 70.83; H, 7.48; N, 18.65; O, 3.04

Price and Availability

Size Price Availability Quantity
5.0mg USD 595.0 2 Weeks
10.0mg USD 1055.0 2 Weeks
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Synonym: YKL-06-062; YKL 06-062; YKL06-062; YKL-06062; YKL 06062; YKL06062;

IUPAC/Chemical Name: 1-Cyclohexyl-3-(2,6-dimethylphenyl)-7-(4-(4-methylpiperazin-1-yl)phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one


InChi Code: InChI=1S/C31H39N7O/c1-22-8-7-9-23(2)28(22)37-21-24-20-32-30(34-29(24)38(31(37)39)27-10-5-4-6-11-27)33-25-12-14-26(15-13-25)36-18-16-35(3)17-19-36/h7-9,12-15,20,27H,4-6,10-11,16-19,21H2,1-3H3,(H,32,33,34)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 525.701 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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