WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561804

CAS#: 1202388-64-4

Description: IAXO-101 interferes with human, rat and mouse TLR4/CD14 signaling.

Chemical Structure

CAS# 1202388-64-4

Theoretical Analysis

MedKoo Cat#: 561804
Name: IAXO-101
CAS#: 1202388-64-4
Chemical Formula: C42H84INO5
Exact Mass: 0.00
Molecular Weight: 810.040
Elemental Analysis: C, 62.28; H, 10.45; I, 15.67; N, 1.73; O, 9.88

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: IAXO-101; IAXO 101; IAXO101;

IUPAC/Chemical Name: N-(((2R,3R,4S,5R,6S)-3-hydroxy-6-methoxy-4,5-bis(tetradecyloxy)tetrahydro-2H-pyran-2-yl)methyl)-N,N-dimethylcyclopentanaminium iodide


InChi Code: InChI=1S/C42H84NO5.HI/c1-6-8-10-12-14-16-18-20-22-24-26-30-34-46-40-39(44)38(36-43(3,4)37-32-28-29-33-37)48-42(45-5)41(40)47-35-31-27-25-23-21-19-17-15-13-11-9-7-2;/h37-42,44H,6-36H2,1-5H3;1H/q+1;/p-1/t38-,39-,40+,41-,42+;/m1./s1


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 810.040000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Hermann JK, Ravikumar M, Shoffstall A, Ereifej ES, Kovach K, Chang J, Soffer A, Wong CT, Srivastava V, Smith P, Protasiewicz G, Jiang J, Selkirk S, Miller RH, Sidik S, Ziats NP, Taylor D, Capadona JR. Inhibition of the cluster of differentiation 14 innate immunity pathway with IAXO-101 improves chronic microelectrode performance. J Neural Eng. 2017 Dec 8. doi: 10.1088/1741-2552/aaa03e. [Epub ahead of print] PubMed PMID: 29219114. 2: Barboza R, Lima FA, Reis AS, Murillo OJ, Peixoto EPM, Bandeira CL, Fotoran WL, Sardinha LR, Wunderlich G, Bevilacqua E, Lima MRD, Alvarez JM, Costa FTM, Gonçalves LA, Epiphanio S, Marinho CRF. TLR4-Mediated Placental Pathology and Pregnancy Outcome in Experimental Malaria. Sci Rep. 2017 Aug 17;7(1):8623. doi: 10.1038/s41598-017-08299-x. PubMed PMID: 28819109; PubMed Central PMCID: PMC5561130.