WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 527499
Description: ZM39923 HCl is a potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3).
MedKoo Cat#: 527499
Name: ZM39923 HCl
Chemical Formula: C23H26ClNO
Exact Mass: 367.1703
Molecular Weight: 367.917
Elemental Analysis: C, 75.09; H, 7.12; Cl, 9.64; N, 3.81; O, 4.35
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: ZM 39923; ZM-39923; ZM39923 HCl
IUPAC/Chemical Name: 3-[Benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one hydrochloride
InChi Key: NJTUORMLOPXPBY-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H25NO.ClH/c1-18(2)24(17-19-8-4-3-5-9-19)15-14-23(25)22-13-12-20-10-6-7-11-21(20)16-22;/h3-13,16,18H,14-15,17H2,1-2H3;1H
SMILES Code: O=C(C1=CC=C2C=CC=CC2=C1)CCN(CC3=CC=CC=C3)C(C)C.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 367.917 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Vidro-Kotchan E, Yendluri BB, Le-Thai T, Tsin A. NBHA reduces acrolein-induced changes in ARPE-19 cells: possible involvement of TGFβ. Curr Eye Res. 2011 Apr;36(4):370-8. doi: 10.3109/02713683.2010.549601. Epub 2011 Feb 10. PubMed PMID: 21309688; PubMed Central PMCID: PMC4487514.