WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 527492
CAS#: 1231220-79-3
Description: LY2828360 is a novel potent, selective, and efficacious CB2 agonist.
MedKoo Cat#: 527492
Name: LY2828360
CAS#: 1231220-79-3
Chemical Formula: C22H27ClN6O
Exact Mass: 426.1935
Molecular Weight: 426.949
Elemental Analysis: C, 61.89; H, 6.37; Cl, 8.30; N, 19.68; O, 3.75
Synonym: LY 2828360; LY-2828360; LY2828360
IUPAC/Chemical Name: 8-(2-Chloro-phenyl)-2-methyl-6-(4-methyl-piperazin-1-yl)-9-(tetrahydro-pyran-4-yl)-9H-purine
InChi Key: UCMNDPDJRSEZPL-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H27ClN6O/c1-15-24-21(28-11-9-27(2)10-12-28)19-22(25-15)29(16-7-13-30-14-8-16)20(26-19)17-5-3-4-6-18(17)23/h3-6,16H,7-14H2,1-2H3
SMILES Code: CN1CCN(C2=C3N=C(C4=CC=CC=C4Cl)N(C5CCOCC5)C3=NC(C)=N2)CC1
1: Lin X, Dhopeshwarkar AS, Huibregtse M, Mackie K, Hohmann AG. Slowly Signaling G Protein-Biased CB(2) Cannabinoid Receptor Agonist LY2828360 Suppresses Neuropathic Pain with Sustained Efficacy and Attenuates Morphine Tolerance and Dependence. Mol Pharmacol. 2018 Feb;93(2):49-62. doi: 10.1124/mol.117.109355. Epub 2017 Nov 30. PubMed PMID: 29192123.