Pyridoxine 5'-phosphate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561780

CAS#: 8059-24-3

Description: Pyridoxine 5'-phosphate is an enzyme cofactor in the biosynthesis of five important neurotransmitters: serotonin, dopamine, epinephrine, norepinephrine, and gamma-aminobutyric acid (GABA).


Chemical Structure

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Pyridoxine 5'-phosphate
CAS# 8059-24-3

Theoretical Analysis

MedKoo Cat#: 561780
Name: Pyridoxine 5'-phosphate
CAS#: 8059-24-3
Chemical Formula: C8H12NO5P
Exact Mass: 233.05
Molecular Weight: 233.150
Elemental Analysis: C, 41.21; H, 5.19; N, 6.01; O, 34.31; P, 13.28

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Pyridoxine 5'-phosphate; PLP; Vitamin B6;

IUPAC/Chemical Name: (5-hydroxy-4,6-dimethylpyridin-3-yl)methyl dihydrogen phosphate

InChi Key: RBCOYOYDYNXAFA-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H12NO5P/c1-5-7(4-14-15(11,12)13)3-9-6(2)8(5)10/h3,10H,4H2,1-2H3,(H2,11,12,13)

SMILES Code: O=P(O)(O)OCC1=C(C)C(O)=C(C)N=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 233.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Rosenberg J, Ischebeck T, Commichau FM. Vitamin B6 metabolism in microbes and approaches for fermentative production. Biotechnol Adv. 2017 Jan - Feb;35(1):31-40. doi: 10.1016/j.biotechadv.2016.11.004. Epub 2016 Nov 24. Review. PubMed PMID: 27890703.

2: di Salvo ML, Safo MK, Contestabile R. Biomedical aspects of pyridoxal 5'-phosphate availability. Front Biosci (Elite Ed). 2012 Jan 1;4:897-913. Review. PubMed PMID: 22201923.

3: di Salvo ML, Contestabile R, Safo MK. Vitamin B(6) salvage enzymes: mechanism, structure and regulation. Biochim Biophys Acta. 2011 Nov;1814(11):1597-608. doi: 10.1016/j.bbapap.2010.12.006. Epub 2010 Dec 20. Review. PubMed PMID: 21182989.

4: Garrido-Franco M. Pyridoxine 5'-phosphate synthase: de novo synthesis of vitamin B6 and beyond. Biochim Biophys Acta. 2003 Apr 11;1647(1-2):92-7. Review. PubMed PMID: 12686115.

5: di Salvo ML, Safo MK, Musayev FN, Bossa F, Schirch V. Structure and mechanism of Escherichia coli pyridoxine 5'-phosphate oxidase. Biochim Biophys Acta. 2003 Apr 11;1647(1-2):76-82. Review. PubMed PMID: 12686112.