WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 571450
CAS#: 72548-16-4
Description: Acantholide is a Sesquiterpene lactone from Acanthospermum glabratum. It has been investigated for anticancer effects, but none were found. It is toxic to humans.
MedKoo Cat#: 571450
Name: Acantholide
CAS#: 72548-16-4
Chemical Formula: C19H24O6
Exact Mass: 348.1573
Molecular Weight: 348.4
Elemental Analysis: C, 65.50; H, 6.94; O, 27.55
This product is not in stock, which may be available by custom synthesis.
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Synonym: Acantholide; NSC 277282; NSC277282; NSC-277282
IUPAC/Chemical Name: Propanoic acid, 2-methyl-, 6-formyl-2,3,3a,4,5,8,9,11a-octahydro-4-hydroxy-10-methyl-3-methylene-2-oxocyclodeca(b)furan-5-yl ester, (3aR-(3aR*,4S*,5S*,6E,10E,11aR*))-
InChi Key: MWYCMNPDBWRCKB-XJZCXBHUSA-N
InChi Code: InChI=1S/C19H24O6/c1-10(2)18(22)25-17-13(9-20)7-5-6-11(3)8-14-15(16(17)21)12(4)19(23)24-14/h7-10,14-17,21H,4-6H2,1-3H3/b11-8+,13-7-/t14-,15+,16+,17+/m1/s1
SMILES Code: CC(C)C(O[C@@H](/C(C=O)=C\CC/C(C)=C/1)[C@@H](O)[C@](C2=C)([H])[C@]1([H])OC2=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 348.4 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Lotter H, Wagner H, Saleh AA, Cordell GA, Farnsworth NR. Potential anticancer agents, XI. X-ray structure determination of acantholide. Z Naturforsch C. 1979 Sep-Oct;34(9-10):677-82. PubMed PMID: 160692.
