BFE-55

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584162

CAS#: 21151-91-7

Description: BFE-55 is derivative of befunolol (a beta-adrenergic partial agonist). BFE-55 interacts with only the high affinity sites in beta-adrenoceptors

Chemical Structure

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BFE-55
CAS# 21151-91-7
Instruction

Theoretical Analysis

MedKoo Cat#: 584162
Name: BFE-55
CAS#: 21151-91-7
Chemical Formula: C14H19NO3
Exact Mass: 249.14
Molecular Weight: 249.310
Elemental Analysis: C, 67.45; H, 7.68; N, 5.62; O, 19.25

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: BFE-55; BFE55; BFE 55.

IUPAC/Chemical Name: 2-Propanol, 1-(7-benzofuranyloxy)-3-((1-methylethyl)amino)-

InChi Key: JSBPDRDKVNCRIK-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H19NO3/c1-10(2)15-8-12(16)9-18-13-5-3-4-11-6-7-17-14(11)13/h3-7,10,12,15-16H,8-9H2,1-2H3

SMILES Code: OC(CNC(C)C)COC1=C(OC=C2)C2=CC=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 249.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Takayanagi I, Ogishima M, Koike K, Hisayama T, Hayashida M, Fujii M. Dose difference in beta-adrenergic blockers with intrinsic sympathomimetic action to block beta-adrenoceptors and induce sympathomimetic action. Gen Pharmacol. 1989;20(4):417-9. PubMed PMID: 2568966.

2: Takayanagi I, Koike K, Ogishima M, Hayashida M, Fujii M. Effect of histamine on two different affinity sites in beta-adrenoceptors. Gen Pharmacol. 1989;20(2):219-22. PubMed PMID: 2565848.

3: Koike K, Nakagoshi A, Takayanagi I. A derivative of befunolol, BFE-55, interacts with only the high affinity sites in beta-adrenoceptors. Can J Physiol Pharmacol. 1987 Oct;65(10):2150-3. PubMed PMID: 2827874.

4: Koike K, Takayanagi I. Interactions of befunolol, a beta-adrenergic partial agonist, and its derivatives with high and low affinity sites in beta-adrenoceptors. J Pharmacobiodyn. 1987 Sep;10(9):494-8. PubMed PMID: 2893834.

5: Takayanagi I, Koike K, Nakagoshi A. Interactions of some partial agonists with high and low affinity binding sites in beta-adrenoceptors. Can J Physiol Pharmacol. 1987 Jan;65(1):18-22. PubMed PMID: 2882827.