WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 527462
CAS#: 1502816-23-0
Description: MS049 is a potent and selective inhibitor of PRMT4,6 and is active in cells.
MedKoo Cat#: 527462
Name: MS049
CAS#: 1502816-23-0
Chemical Formula: C15H24N2O
Exact Mass: 248.1889
Molecular Weight: 248.37
Elemental Analysis: C, 72.54; H, 9.74; N, 11.28; O, 6.44
Synonym: MS049; MS-049; MS 049.
IUPAC/Chemical Name: [2-(4-Benzyloxy-piperidin-1-yl)-ethyl]-methyl-amine
InChi Key: HBOJWAYLSJLULG-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H24N2O/c1-16-9-12-17-10-7-15(8-11-17)18-13-14-5-3-2-4-6-14/h2-6,15-16H,7-13H2,1H3
SMILES Code: CNCCN1CCC(OCC2=CC=CC=C2)CC1
1: Shen Y, Szewczyk MM, Eram MS, Smil D, Kaniskan HÜ, de Freitas RF, Senisterra G, Li F, Schapira M, Brown PJ, Arrowsmith CH, Barsyte-Lovejoy D, Liu J, Vedadi M, Jin J. Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6. J Med Chem. 2016 Oct 13;59(19):9124-9139. doi: 10.1021/acs.jmedchem.6b01033. Epub 2016 Sep 15. PubMed PMID: 27584694; PubMed Central PMCID: PMC5063716.