WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 527452
Description: YZ51 is a novel potent inhibitor of ribonucleotide reductase (RR), inhibiting hepatitis B virus replication by targeting ribonucleotide reductase M2 protein.
MedKoo Cat#: 527452
Chemical Formula: C16H14FNO2
Exact Mass: 271.1009
Molecular Weight: 271.2914
Elemental Analysis: C, 70.84; H, 5.20; F, 7.00; N, 5.16; O, 11.79
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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IUPAC/Chemical Name: 4-Cyclopropyl-2-fluoro-N-(4-hydroxyphenyl) benzamide
InChi Key: MWPGUZTXBTYJCD-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H14FNO2/c17-15-9-11(10-1-2-10)3-8-14(15)16(20)18-12-4-6-13(19)7-5-12/h3-10,19H,1-2H2,(H,18,20)
SMILES Code: O=C(NC1=CC=C(O)C=C1)C2=CC=C(C3CC3)C=C2F
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 271.2914 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Liu X, Xu Z, Hou C, Wang M, Chen X, Lin Q, Song R, Lou M, Zhu L, Qiu Y, Chen Z, Yang C, Zhu W, Shao J. Inhibition of hepatitis B virus replication by targeting ribonucleotide reductase M2 protein. Biochem Pharmacol. 2016 Mar 1;103:118-28. doi: 10.1016/j.bcp.2016.01.003. Epub 2016 Jan 13. PubMed PMID: 26774458.