WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 527098

CAS#: 71939-12-3

Description: O4 is a novel stabilizer of amyloid-ß fibrils, accelerating the formation of end-stage mature fibrils.

Chemical Structure

CAS# 71939-12-3

Theoretical Analysis

MedKoo Cat#: 527098
Name: O4
CAS#: 71939-12-3
Chemical Formula: C24H17NO7
Exact Mass: 431.10
Molecular Weight: 431.400
Elemental Analysis: C, 66.82; H, 3.97; N, 3.25; O, 25.96

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: O4; O-4; O 4

IUPAC/Chemical Name: 7-Hydroxy-3,6-bis(2,4-dihydroxyphenyl)-2-phenoxazone


InChi Code: InChI=1S/C24H17NO7/c26-11-1-3-13(19(29)7-11)15-9-22-17(10-21(15)31)25-16-5-6-18(28)23(24(16)32-22)14-4-2-12(27)8-20(14)30/h1-10,15,25-30H


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 431.400000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Salpin JY, Latrous L, Haldys V, Lamsabhi AM. Interactions of Dimethyltin(IV) With Uracil as Studied in the Gas Phase. J Phys Chem A. 2018 Jan 2. doi: 10.1021/acs.jpca.7b11510. [Epub ahead of print] PubMed PMID: 29293002. 2: Lin YL, Chu JH, Lu HJ, Liu N, Wu ZQ. Facile Synthesis of Optically Active and Magnetic Nanoparticles Carrying Helical Poly(phenyl isocyanide) Arms and Their Application in Enantioselective Crystallization. Macromol Rapid Commun. 2018 Jan 2. doi: 10.1002/marc.201700685. [Epub ahead of print] PubMed PMID: 29292546. 3: He L, Song Z, Jia X, Xia Z, Liu Q. Control of Luminescence in Eu(2+)-Doped Orthosilicate-Orthophosphate Phosphors by Chainlike Polyhedra and Electronic Structures. Inorg Chem. 2017 Dec 29. doi: 10.1021/acs.inorgchem.7b02431. [Epub ahead of print] PubMed PMID: 29286659. 4: Liang X, Ma R, Hao L, Wang C, Wu Q, Wang Z. β-Cyclodextrin polymer@Fe(3) O(4) based magnetic solid-phase extraction coupled with HPLC for the determination of benzoylurea insecticides from honey, tomato, and environmental water samples. J Sep Sci. 2017 Dec 27. doi: 10.1002/jssc.201701197. [Epub ahead of print] PubMed PMID: 29280564. 5: Chu Y, Guo L, Xi B, Feng Z, Wu F, Lin Y, Liu J, Sun D, Feng J, Qian Y, Xiong S. Embedding MnO@Mn(3) O(4) Nanoparticles in an N-Doped-Carbon Framework Derived from Mn-Organic Clusters for Efficient Lithium Storage. Adv Mater. 2017 Dec 22. doi: 10.1002/adma.201704244. [Epub ahead of print] PubMed PMID: 29271501. 6: Jang JT, Lee J, Seon J, Ju E, Kim M, Kim YI, Kim MG, Takemura Y, Arbab AS, Kang KW, Park KH, Paek SH, Bae S. Giant Magnetic Heat Induction of Magnesium-Doped γ-Fe(2) O(3) Superparamagnetic Nanoparticles for Completely Killing Tumors. Adv Mater. 2017 Dec 20. doi: 10.1002/adma.201704362. [Epub ahead of print] PubMed PMID: 29266514. 7: Chen B, Ben L, Yu H, Chen Y, Huang X. Understanding Surface Structural Stabilization of the High-Temperature and High-Voltage Cycling Performance of Al(3+)-Modified LiMn(2)O(4) Cathode Material. ACS Appl Mater Interfaces. 2018 Jan 2. doi: 10.1021/acsami.7b14535. [Epub ahead of print] PubMed PMID: 29265811. 8: Li P, Liu Q, Luo H, Liang K, Yi J, Luo Y, Hu Y, Han Y, Kong Q. O-Serotype Conversion in Salmonella Typhimurium Induces Protective Immune Responses against Invasive Non-Typhoidal Salmonella Infections. Front Immunol. 2017 Dec 4;8:1647. doi: 10.3389/fimmu.2017.01647. eCollection 2017. PubMed PMID: 29255460; PubMed Central PMCID: PMC5722840. 9: Uebe R, Keren-Khadmy N, Zeytuni N, Katzmann E, Navon Y, Davidov G, Bitton R, Plitzko JM, Schüler D, Zarivach R. The dual role of MamB in magnetosome membrane assembly and magnetite biomineralization. Mol Microbiol. 2017 Dec 15. doi: 10.1111/mmi.13899. [Epub ahead of print] PubMed PMID: 29243866. 10: Chateau A, Lunderberg JM, Oh SY, Abshire T, Friedlander A, Quinn CP, Missiakas DM, Schneewind O. Galactosylation of the secondary cell wall polysaccharide of Bacillus anthracis and its contribution to anthrax pathogenesis. J Bacteriol. 2017 Dec 11. pii: JB.00562-17. doi: 10.1128/JB.00562-17. [Epub ahead of print] PubMed PMID: 29229702. 11: Sun J, Xu B, Mu Y, Ma H, Qu W. Functional Magnetic Nanoparticles for Highly Efficient Cholesterol Removal. J Food Sci. 2017 Dec 11. doi: 10.1111/1750-3841.13999. [Epub ahead of print] PubMed PMID: 29227533. 12: Huang YF, Liu QH, Li K, Li Y, Chang N. Magnetic iron(III)-based framework composites for the magnetic solid-phase extraction of fungicides from environmental water samples. J Sep Sci. 2017 Dec 11. doi: 10.1002/jssc.201700927. [Epub ahead of print] PubMed PMID: 29227028. 13: Salam T, Premila Devi S, Duncan Lyngdoh RH. Molecular criteria for mutagenesis by DNA methylation: Some computational elucidations. Mutat Res. 2017 Nov 10;807:10-20. doi: 10.1016/j.mrfmmm.2017.10.004. [Epub ahead of print] PubMed PMID: 29220701. 14: Tiwari P, Agarwal S, Srivastava S, Jain S. The combined effect of thermal and chemotherapy on HeLa cells using magnetically actuated smart textured fibrous system. J Biomed Mater Res B Appl Biomater. 2018 Jan;106(1):40-51. doi: 10.1002/jbm.b.33812. Epub 2016 Nov 7. PubMed PMID: 29218857. 15: Liu H, Li Q, Yao Z, Li L, Li Y, Wolverton C, Hersam MC, Wu J, Dravid VP. Origin of Fracture-Resistance to Large Volume Change in Cu-Substituted Co(3) O(4) Electrodes. Adv Mater. 2017 Dec 6. doi: 10.1002/adma.201704851. [Epub ahead of print] PubMed PMID: 29210479. 16: Li Y, Zhong C, Liu J, Zeng X, Qu S, Han X, Deng Y, Hu W, Lu J. Atomically Thin Mesoporous Co(3) O(4) Layers Strongly Coupled with N-rGO Nanosheets as High-Performance Bifunctional Catalysts for 1D Knittable Zinc-Air Batteries. Adv Mater. 2017 Dec 6. doi: 10.1002/adma.201703657. [Epub ahead of print] PubMed PMID: 29210114. 17: Wei C, Liu K, Tao J, Kang X, Hou H, Cheng C, Zhang D. Self-Template Synthesis of Hybrid Porous Co(3) O(4) -CeO(2) Hollow Polyhedrons for High-Performance Supercapacitors. Chem Asian J. 2017 Dec 5. doi: 10.1002/asia.201701582. [Epub ahead of print] PubMed PMID: 29205935. 18: Chen JY, Huang CW, Wu WW. Solid-State Diffusional Behaviors of Functional Metal Oxides at Atomic Scale. Small. 2017 Dec 4. doi: 10.1002/smll.201702877. [Epub ahead of print] PubMed PMID: 29205879. 19: Zheng Z, Xu H, Xu Z, Ge J. A Monodispersed Spherical Zr-Based Metal-Organic Framework Catalyst, Pt/Au@Pd@UIO-66, Comprising an Au@Pd Core-Shell Encapsulated in a UIO-66 Center and Its Highly Selective CO(2) Hydrogenation to Produce CO. Small. 2017 Dec 4. doi: 10.1002/smll.201702812. [Epub ahead of print] PubMed PMID: 29205859. 20: Wang Y, Wei G, Zhang X, Huang X, Zhao J, Guo X, Zhou S. Multistage Targeting Strategy Using Magnetic Composite Nanoparticles for Synergism of Photothermal Therapy and Chemotherapy. Small. 2017 Dec 4. doi: 10.1002/smll.201702994. [Epub ahead of print] PubMed PMID: 29205795.