N6-Allyladenosine

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MedKoo CAT#: 561737

CAS#: 15763-12-9

Description: N6-Allyladenosine is an RNA labeling probe that acts through both metabolic and enzyme-assisted manners.


Chemical Structure

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N6-Allyladenosine
CAS# 15763-12-9

Theoretical Analysis

MedKoo Cat#: 561737
Name: N6-Allyladenosine
CAS#: 15763-12-9
Chemical Formula: C13H17N5O4
Exact Mass: 307.13
Molecular Weight: 307.310
Elemental Analysis: C, 50.81; H, 5.58; N, 22.79; O, 20.82

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: N6-Allyladenosine; N6 Allyladenosine; a6A; N-Allyladenosine; N Allyladenosine;

IUPAC/Chemical Name: (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-[6-(prop-2-enylamino)purin-9-yl]oxolane-3,4-diol

InChi Key: WTYYPLSFICPDGL-QYVSTXNMSA-N

InChi Code: InChI=1S/C13H17N5O4/c1-2-3-14-11-8-12(16-5-15-11)18(6-17-8)13-10(21)9(20)7(4-19)22-13/h2,5-7,9-10,13,19-21H,1,3-4H2,(H,14,15,16)/t7-,9-,10-,13-/m1/s1

SMILES Code: O[C@@H]1[C@@H](CO)O[C@@H](N2C=NC3=C(NCC=C)N=CN=C23)[C@@H]1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 307.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Shu X, Dai Q, Wu T, Bothwell IR, Yue Y, Zhang Z, Cao J, Fei Q, Luo M, He C, Liu J. N(6)-Allyladenosine: A New Small Molecule for RNA Labeling Identified by Mutation Assay. J Am Chem Soc. 2017 Dec 6;139(48):17213-17216. doi: 10.1021/jacs.7b06837. Epub 2017 Nov 15. PubMed PMID: 29116772.

2: Dassano A, Mancuso M, Giardullo P, De Cecco L, Ciuffreda P, Santaniello E, Saran A, Dragani TA, Colombo F. N(6)-isopentenyladenosine and analogs activate the NRF2-mediated antioxidant response. Redox Biol. 2014 Mar 6;2:580-9. doi: 10.1016/j.redox.2014.03.001. eCollection 2014. PubMed PMID: 24688894; PubMed Central PMCID: PMC3969604.

3: Spector T, Beacham LM 3rd. Guanosine monophosphate synthetase from Escherichia coli B-96. Inhibition by nucleosides. J Biol Chem. 1975 Apr 25;250(8):3101-7. PubMed PMID: 164459.