WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 571438
Description: AC 915 is a sigma-1 antagonist investigated in antitumor research.
MedKoo Cat#: 571438
Name: AC 915
Chemical Formula: C14H17Cl2NO2
Exact Mass: 301.0636
Molecular Weight: 302.2
Elemental Analysis: C, 55.64; H, 5.67; Cl, 23.46; N, 4.64; O, 10.59
This product is not in stock, which may be available by custom synthesis.
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Synonym: AC 915; AC-915; AC915
IUPAC/Chemical Name: Benzeneacetic acid, 3,4-dichloro-, 2-(1-pyrrolidinyl)ethyl ester
InChi Key: CYVORFBBJKNNDO-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H17Cl2NO2/c15-12-4-3-11(9-13(12)16)10-14(18)19-8-7-17-5-1-2-6-17/h3-4,9H,1-2,5-8,10H2
SMILES Code: O=C(OCCN1CCCC1)CC2=CC=C(Cl)C(Cl)=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 302.2 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Rybczynska AA, Dierckx RA, Ishiwata K, Elsinga PH, van Waarde A. Cytotoxicity of sigma-receptor ligands is associated with major changes of cellular metabolism and complete occupancy of the sigma-2 subpopulation. J Nucl Med. 2008 Dec;49(12):2049-56. doi: 10.2967/jnumed.108.053876. Epub 2008 Nov 7. PubMed PMID: