WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571362

CAS#: 880759-45-5

Description: M1000907 is a selective 5-HT2A receptor antagonist. It may interfere with altered 5-HT2A receptor signaling that contributes to ASD symptoms. Increased 5-HT2A receptor activity in certain brain regions may contribute to repetitive behaviors, so treatment with a selective 5-HT2A receptor antagonist has been proposed to improve cognitive flexibility in individuals with ASD.

Chemical Structure

CAS# 880759-45-5

Theoretical Analysis

MedKoo Cat#: 571362
Name: M1000907
CAS#: 880759-45-5
Chemical Formula: C22H28FNO3
Exact Mass: 373.2053
Molecular Weight: 373.47
Elemental Analysis: C, 70.75; H, 7.56; F, 5.09; N, 3.75; O, 12.85

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: M1000907; M-1000907; M 1000907

IUPAC/Chemical Name: α-(3,4-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidine methanol


InChi Code: InChI=1S/C22H28FNO3/c1-26-20-8-5-18(15-21(20)27-2)22(25)17-10-13-24(14-11-17)12-9-16-3-6-19(23)7-4-16/h3-8,15,17,22,25H,9-14H2,1-2H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 373.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Lacivita E, Perrone R, Margari L, Leopoldo M. Targets for Drug Therapy for Autism Spectrum Disorder: Challenges and Future Directions. J Med Chem. 2017 Oct 30. doi: 10.1021/acs.jmedchem.7b00965. [Epub ahead of print] PubMed PMID: 29039668.