WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 571352
Description: ABD-295 is an antiresorptive agent, osteoclast inhibitor, and novel biphenylsulfide derivative with potent inhibitory effects on osteoclastic bone resorption in vitro. It has been shown to prevent ovariectomy-induced bone loss in vivo.
MedKoo Cat#: 571352
Chemical Formula: C17H19F2NO3S
Exact Mass: 355.1054
Molecular Weight: 355.4
Elemental Analysis: C, 57.45; H, 5.39; F, 10.69; N, 3.94; O, 13.51; S, 9.02
Synonym: ABD-295; ABD295; ABD 295
IUPAC/Chemical Name: (1,1'-Biphenyl)-4-sulfonamide, 2',4'-difluoro-N-(4-hydroxybutyl)-2-methyl-
InChi Key: TYHUSNQWWKFBCU-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H19F2NO3S/c1-12-10-14(24(22,23)20-8-2-3-9-21)5-7-15(12)16-6-4-13(18)11-17(16)19/h4-7,10-11,20-21H,2-3,8-9H2,1H3
SMILES Code: O=S(C1=CC=C(C2=CC=C(F)C=C2F)C(C)=C1)(NCCCCO)=O
1: Greig IR, Idris AI, Ralston SH, van't Hof RJ. Development and characterization of biphenylsulfonamides as novel inhibitors of bone resorption. J Med Chem. 2006 Dec 14;49(25):7487-92. PubMed PMID: 17149877.