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MedKoo CAT#: 561507

CAS#: 862974-25-2

Description: N106 directly activates the SUMO-activating enzyme, E1 ligase, and triggers intrinsic SUMOylation of SERCA2a. Decreased activity and expression of the cardiac sarcoplasmic reticulum calcium ATPase (SERCA2a), a critical pump regulating calcium cycling in cardiomyocyte, are hallmarks of heart failure.

Price and Availability

Size Price Shipping out time Quantity
5mg USD 295 2 Weeks
10mg USD 505 2 Weeks
25mg USD 855 2 Weeks
50mg USD 1600 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-07-16. Prices are subject to change without notice.

N106, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 561507
Name: N106
CAS#: 862974-25-2
Chemical Formula: C17H14N4O3S
Exact Mass: 354.0787
Molecular Weight: 354.38
Elemental Analysis: C, 57.62; H, 3.98; N, 15.81; O, 13.54; S, 9.05

Synonym: N106; N-106; N 106;

IUPAC/Chemical Name: N-(4-methoxybenzo[d]thiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine


InChi Code: InChI=1S/C17H14N4O3S/c1-22-11-8-6-10(7-9-11)15-20-21-16(24-15)19-17-18-14-12(23-2)4-3-5-13(14)25-17/h3-9H,1-2H3,(H,18,19,21)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Kho C, Lee A, Jeong D, Oh JG, Gorski PA, Fish K, Sanchez R, DeVita RJ, Christensen G, Dahl R, Hajjar RJ. Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure. Nat Commun. 2015 Jun 12;6:7229. doi: 10.1038/ncomms8229. PubMed PMID: 26068603; PubMed Central PMCID: PMC4467461.