WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561471

CAS#: 675132-92-0

Description: Oe-9000 is a novel blocker of voltage-gated Na(+) currents in neurons. It reversibly reduces slowly activating and inactivating tetrodotoxin-resistant (TTX-R) Na(+) currents as well as rapidly activating and inactivating TTX-sensitive (TTX-S) Na(+) currents at low micromolar concentrations.

Chemical Structure

CAS# 675132-92-0

Theoretical Analysis

MedKoo Cat#: 561471
Name: Oe-9000
CAS#: 675132-92-0
Chemical Formula: C21H29NO3
Exact Mass: 343.2147
Molecular Weight: 343.47
Elemental Analysis: C, 73.44; H, 8.51; N, 4.08; O, 13.97

Price and Availability

Size Price Availability Quantity
5.0g USD 6350.0 2 Weeks
25.0g USD 22550.0 2 Weeks
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Synonym: Oe-9000; Oe 9000; Oe9000;

IUPAC/Chemical Name: 2,2'-((4-(4-(phenoxymethyl)phenyl)butyl)azanediyl)bis(ethan-1-ol)


InChi Code: InChI=1S/C21H29NO3/c23-16-14-22(15-17-24)13-5-4-6-19-9-11-20(12-10-19)18-25-21-7-2-1-3-8-21/h1-3,7-12,23-24H,4-6,13-18H2


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 343.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Baumgart M, Feller C, Natura G, Dahse T, Schaible HG, Dahse I. Blockade of TTX-resistant and TTX-sensitive Na+ currents in cultured dorsal root ganglion neurons by fomocaine and the fomocaine derivative Oe 9000. Brain Res. 2010 Oct 28;1358:54-63. doi: 10.1016/j.brainres.2010.08.033. Epub 2010 Aug 19. PubMed PMID: 20727863.

2: Dahse T, Wennek-Klose J, Listing M, Fleck C, Oelschläger H. [In vitro investigations of phase I metabolism of the fomocaine derivative Oe 9000 with pig liver homogenates]. Pharmazie. 2006 Nov;61(11):943-51. German. PubMed PMID: 17152988.

3: Fleck C, Wennek-Klose J, Wange J, Oelschläger H. Effects and toxicity of new fomocaine derivatives and of 2-hydroxypropyl-beta-cyclodextrin inclusion compounds in rats. Arzneimittelforschung. 2004;54(5):265-74. PubMed PMID: 15212188.

4: Fleck C, Karge E, Loy S, Wennek-Klose J, Listing M, Oelschläger H. Local anaesthetic effects and toxicity of seven new diethanolamine and morpholine derivatives of fomocaine. Testing in rats compared with procaine and tetracaine. Arzneimittelforschung. 2003;53(3):221-8. PubMed PMID: 12705179.


5.0g / USD 6350.0