WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 329823
Description: Lanolin, also known as wool wax or wool grease, is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid. Lanolin contains a complex combination of esters and polyesters, consisting chiefly of cholesteryl and isocholesteryl esters of the higher fatty acids. Lanolin and its many derivatives are used extensively in both the personal care (e.g., high value cosmetics, facial cosmetics, lip products) and health care sectors such as topical liniments. Lanolin is also found in lubricants, rust-preventive coatings, shoe polish, and other commercial products. Lanolin is a relatively common allergen and is often misunderstood as a wool allergy. However, allergy to a lanolin-containing product is difficult to pinpoint and often other products containing lanolin may be fine for use. Patch testing can be done if a lanolin allergy is suspected.
MedKoo Cat#: 329823
Related CAS #: 114471-15-7; 8036-05-3 8038-41-3 8038-43-5 8040-96-8 8006-54-0
Synonym: Lanolin, wool wax or wool grease; Anhydrous lanolin; Dewaxed lanolin.
IUPAC/Chemical Name: N/A (mixture)
InChi Key: N/A
InChi Code: N/A
SMILES Code: N/A
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
A typical high purity grade of lanolin is composed predominantly of long chain waxy esters (approximately 97% by weight) the remainder being lanolin alcohols, lanolin acids and lanolin hydrocarbons.
An estimated 8,000 to 20,000 different types of lanolin esters are present in lanolin, resulting from combinations between the 200 or so different lanolin acids and the 100 or so different lanolin alcohols identified so far.
Lanolin’s complex composition of long chain esters, hydroxy esters, diesters, lanolin alcohols, and lanolin acids means in addition to it being a valuable product in its own right, it is also the starting point for the production of a whole spectrum of lanolin derivatives, which possess wide-ranging chemical and physical properties. The main derivatisation routes include hydrolysis, fractional solvent crystallisation, esterification, hydrogenation, and alkoxylation and quaternisation.Lanolin derivatives obtained from these processes are used widely in both high-value cosmetics and skin treatment products.
Hydrolysis of lanolin yields lanolin alcohols and lanolin acids. Lanolin alcohols are a rich source of cholesterol (an important skin lipid) and are powerful water-in-oil emulsifiers; they have been used extensively in skin care products for over 100 years.Notably, approximately 40% of the acids derived from lanolin are alpha hydroxy acids (AHAs).The use of AHAs in skin care products has attracted a great deal of attention in recent years.