WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530904

CAS#: 189744-46-5

Description: RO10-5824 is a D4-selective partial agonist. RO10-5824 is a potent candidate for the management of cocaine use disorders. The identification of effective medications for the management of cocaine use disorders remains an unmet public health challenge. In view of the prominent role of dopaminergic mechanisms in cocaine's abuse-related effects, research has focused on the development of subtype-selective dopamine D1-4 receptor antagonists.

Price and Availability

Size Price Shipping out time Quantity
100mg USD 1350 2 Weeks
200mg USD 1850 2 Weeks
500mg USD 2650 2 Weeks
1g USD 3450 2 Weeks
2g USD 4850 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-26. Prices are subject to change without notice.

Ro 10-5824, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 530904
Name: RO10-5824
CAS#: 189744-46-5
Chemical Formula: C17H20N4
Exact Mass: 280.1688
Molecular Weight: 280.375
Elemental Analysis: C, 72.83; H, 7.19; N, 19.98

Synonym: RO10-5824; RO 10-5824; RO-10-5824; RO105824; RO 105824; RO-105824.

IUPAC/Chemical Name: 2-methyl-5-((4-phenyl-5,6-dihydropyridin-1(2H)-yl)methyl)pyrimidin-4-amine


InChi Code: InChI=1S/C17H20N4/c1-13-19-11-16(17(18)20-13)12-21-9-7-15(8-10-21)14-5-3-2-4-6-14/h2-7,11H,8-10,12H2,1H3,(H2,18,19,20)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Bergman J, Rheingold CG. Dopamine D₄ Receptor Antagonists for the Treatment of
Cocaine Use Disorders. CNS Neurol Disord Drug Targets. 2015;14(6):707-15. Review.
PubMed PMID: 26022267.

2: Murai T, Nakako T, Ikeda K, Ikejiri M, Ishiyama T, Taiji M. Lack of dopamine
D4 receptor affinity contributes to the procognitive effect of lurasidone. Behav
Brain Res. 2014 Mar 15;261:26-30. doi: 10.1016/j.bbr.2013.11.036. Epub 2013 Dec
1. PubMed PMID: 24304719.