WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561403

CAS#: 2003260-55-5

Description: KDM4B-IN-B3, also know as NCGC00244536, is a novel KDM4 inhibitor. KDM4B-IN-B3 inhibits the in vivo growth of tumors derived from PC3 cells and ex vivo human PCa explants. Histone lysine demethylase KDM4/JMJD2s are overexpressed in many human tumors including prostate cancer (PCa).

Price and Availability

Size Price Shipping out time Quantity
10mg USD 330 2 Weeks
25mg USD 610 2 Weeks
50mg USD 950 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-26. Prices are subject to change without notice.

KDM4B-IN-B3, also know as NCGC00244536, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 561403
Name: KDM4B-IN-B3
CAS#: 2003260-55-5
Chemical Formula: C25H22N2O2
Exact Mass: 382.1681
Molecular Weight: 382.46
Elemental Analysis: C, 78.51; H, 5.80; N, 7.32; O, 8.37

Synonym: KDM4B-IN-B3; KDM4B IN B3; KDM4BINB3; NCGC00244536

IUPAC/Chemical Name: 3-(8-Hydroxyquinolin-6-yl)-N-(3-phenylpropyl)benzamide


InChi Code: InChI=1S/C25H22N2O2/c28-23-17-22(16-20-12-6-13-26-24(20)23)19-10-4-11-21(15-19)25(29)27-14-5-9-18-7-2-1-3-8-18/h1-4,6-8,10-13,15-17,28H,5,9,14H2,(H,27,29)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Duan L, Rai G, Roggero C, Zhang QJ, Wei Q, Ma SH, Zhou Y, Santoyo J, Martinez ED, Xiao G, Raj GV, Jadhav A, Simeonov A, Maloney DJ, Rizo J, Hsieh JT, Liu ZP. KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes. Chem Biol. 2015 Sep 17;22(9):1185-96. doi: 10.1016/j.chembiol.2015.08.007. Epub 2015 Sep 10. PubMed PMID: 26364928; PubMed Central PMCID: PMC4578295.