WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561381

CAS#: 537-42-8

Description: Pterostilbene is an antioxidant that primarily exists in blueberries, grapevines and heartwood of red sandalwood. Pterostilbene also has chemopreventive, antiinflammatory, antidiabetic, antidyslipidemic, antiatherosclerotic and neuroprotective effects.

Chemical Structure

CAS# 537-42-8

Theoretical Analysis

MedKoo Cat#: 561381
Name: Pterostilbene
CAS#: 537-42-8
Chemical Formula: C16H16O3
Exact Mass: 256.1099
Molecular Weight: 256.3
Elemental Analysis: C, 74.98; H, 6.29; O, 18.73

Price and Availability

Size Price Availability Quantity
100.0mg USD 160.0 2 Weeks
1.0g USD 270.0 2 Weeks
Bulk inquiry

Synonym: Pterostilbene; PS;

IUPAC/Chemical Name: 4-[(E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol


InChi Code: InChI=1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3+


Appearance: White to off-white, solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certificate of Analysis:

Safety Data Sheet (SDS):

Preparing Stock Solutions

The following data is based on the product molecular weight 256.3 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Dvorakova M, Landa P. Anti-inflammatory activity of natural stilbenoids: A review. Pharmacol Res. 2017 Aug 9. pii: S1043-6618(17)30870-8. doi: 10.1016/j.phrs.2017.08.002. [Epub ahead of print] Review. PubMed PMID: 28803136.

2: Kumar A, Rimando AM, Levenson AS. Resveratrol and pterostilbene as a microRNA-mediated chemopreventive and therapeutic strategy in prostate cancer. Ann N Y Acad Sci. 2017 Jun 29. doi: 10.1111/nyas.13372. [Epub ahead of print] Review. PubMed PMID: 28662290.

3: Dandawate PR, Subramaniam D, Jensen RA, Anant S. Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy. Semin Cancer Biol. 2016 Oct;40-41:192-208. doi: 10.1016/j.semcancer.2016.09.001. Epub 2016 Sep 5. Review. PubMed PMID: 27609747.

4: Kosuru R, Rai U, Prakash S, Singh A, Singh S. Promising therapeutic potential of pterostilbene and its mechanistic insight based on preclinical evidence. Eur J Pharmacol. 2016 Oct 15;789:229-243. doi: 10.1016/j.ejphar.2016.07.046. Epub 2016 Jul 27. Review. PubMed PMID: 27475678.

5: Giacomini E, Rupiani S, Guidotti L, Recanatini M, Roberti M. The Use of Stilbene Scaffold in Medicinal Chemistry and Multi- Target Drug Design. Curr Med Chem. 2016;23(23):2439-89. Review. PubMed PMID: 27183980.

6: Poulose SM, Thangthaeng N, Miller MG, Shukitt-Hale B. Effects of pterostilbene and resveratrol on brain and behavior. Neurochem Int. 2015 Oct;89:227-33. doi: 10.1016/j.neuint.2015.07.017. Epub 2015 Jul 26. Review. PubMed PMID: 26212523.

7: Belviranli M, Okudan N. Well-Known Antioxidants and Newcomers in Sport Nutrition: Coenzyme Q10, Quercetin, Resveratrol, Pterostilbene, Pycnogenol and Astaxanthin. In: Lamprecht M, editor. Antioxidants in Sport Nutrition. Boca Raton (FL): CRC Press/Taylor & Francis; 2015. Chapter 5. PubMed PMID: 26065085.

8: Bhakkiyalakshmi E, Sireesh D, Rajaguru P, Paulmurugan R, Ramkumar KM. The emerging role of redox-sensitive Nrf2-Keap1 pathway in diabetes. Pharmacol Res. 2015 Jan;91:104-14. doi: 10.1016/j.phrs.2014.10.004. Epub 2014 Oct 29. Review. PubMed PMID: 25447793.

9: Estrela JM, Ortega A, Mena S, Rodriguez ML, Asensi M. Pterostilbene: Biomedical applications. Crit Rev Clin Lab Sci. 2013 May-Jun;50(3):65-78. doi: 10.3109/10408363.2013.805182. Epub 2013 Jul 1. Review. PubMed PMID: 23808710.

10: McCormack D, McFadden D. A review of pterostilbene antioxidant activity and disease modification. Oxid Med Cell Longev. 2013;2013:575482. doi: 10.1155/2013/575482. Epub 2013 Apr 4. Review. PubMed PMID: 23691264; PubMed Central PMCID: PMC3649683.

11: Kasiotis KM, Pratsinis H, Kletsas D, Haroutounian SA. Resveratrol and related stilbenes: their anti-aging and anti-angiogenic properties. Food Chem Toxicol. 2013 Nov;61:112-20. doi: 10.1016/j.fct.2013.03.038. Epub 2013 Apr 6. Review. PubMed PMID: 23567244.

12: Cherniack EP. A berry thought-provoking idea: the potential role of plant polyphenols in the treatment of age-related cognitive disorders. Br J Nutr. 2012 Sep;108(5):794-800. doi: 10.1017/S0007114512000669. Epub 2012 Apr 5. Review. PubMed PMID: 22475317.

13: Aiyer HS, Warri AM, Woode DR, Hilakivi-Clarke L, Clarke R. Influence of berry polyphenols on receptor signaling and cell-death pathways: implications for breast cancer prevention. J Agric Food Chem. 2012 Jun 13;60(23):5693-708. doi: 10.1021/jf204084f. Epub 2012 Feb 22. Review. PubMed PMID: 22300613; PubMed Central PMCID: PMC3383353.

14: McCormack D, McFadden D. Pterostilbene and cancer: current review. J Surg Res. 2012 Apr;173(2):e53-61. doi: 10.1016/j.jss.2011.09.054. Epub 2011 Oct 21. Review. PubMed PMID: 22099605.

15: Chen CF, Li YD, Xu Z. [Chemical principles and bioactivities of blueberry]. Yao Xue Xue Bao. 2010 Apr;45(4):422-9. Review. Chinese. PubMed PMID: 21355205.

16: Pterostilbene. Monograph. Altern Med Rev. 2010 Jul;15(2):159-63. Review. PubMed PMID: 20807001.

17: Mikstacka R, Ignatowicz E. [Chemopreventive and chemotherapeutic effect of trans-resveratrol and its analogues in cancer]. Pol Merkur Lekarski. 2010 Jun;28(168):496-500. Review. Polish. PubMed PMID: 20642113.

18: Rimando AM, Suh N. Biological/chemopreventive activity of stilbenes and their effect on colon cancer. Planta Med. 2008 Oct;74(13):1635-43. doi: 10.1055/s-0028-1088301. Epub 2008 Oct 8. Review. PubMed PMID: 18843589.

19: Roupe KA, Remsberg CM, Yáñez JA, Davies NM. Pharmacometrics of stilbenes: seguing towards the clinic. Curr Clin Pharmacol. 2006 Jan;1(1):81-101. Review. PubMed PMID: 18666380.