lambda-Cyhalothrin
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571231

CAS#: 91465-08-6

Description: lambda-Cyhalothrin is an insecticide and pesticide that has adverse effects on rats as well, including neurotoxic and hepatopancreatic effects.


Chemical Structure

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lambda-Cyhalothrin
CAS# 91465-08-6

Theoretical Analysis

MedKoo Cat#: 571231
Name: lambda-Cyhalothrin
CAS#: 91465-08-6
Chemical Formula: C23H19ClF3NO3
Exact Mass: 449.1006
Molecular Weight: 449.85
Elemental Analysis: C, 61.41; H, 4.26; Cl, 7.88; F, 12.67; N, 3.11; O, 10.67

Price and Availability

Size Price Availability Quantity
10.0mg USD 370.0 2 Weeks
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Synonym: lambda-Cyhalothrin; Icon; Karate

IUPAC/Chemical Name: Cyclopropanecarboxylic acid, 3-((1Z)-2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl-, (R)-cyano(3-phenoxyphenyl)methyl ester, (1S,3S)-rel-

InChi Key: ZXQYGBMAQZUVMI-RDDWSQKMSA-N

InChi Code: InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m1/s1

SMILES Code: O=C([C@@H]1C(C)(C)[C@@H]1/C=C(Cl)/C(F)(F)F)O[C@@H](C#N)C2=CC=CC(OC3=CC=CC=C3)=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 449.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Shen X, Xu Z, Zhang X, Yang F. Stable carbon isotope fractionation during the biodegradation of lambda-cyhalothrin. Sci Total Environ. 2015 Nov 1;532:415-9. doi: 10.1016/j.scitotenv.2015.05.045. Epub 2015 Jun 16. PubMed PMID: 26092290.

2: Elhalwagy ME, Abd-Alrahman SH, Nahas AA, Ziada RM, Mohamady AH. Hepatopancreatic intoxication of lambda cyhalothrin insecticide on albino rats. Int J Clin Exp Med. 2015 May 15;8(5):7297-305. eCollection 2015. PubMed PMID: 26221269; PubMed Central PMCID: PMC4509214.

3: Abbas N, Shad SA. Assessment of resistance risk to lambda-cyhalothrin and cross-resistance to four other insecticides in the house fly, Musca domestica L. (Diptera: Muscidae). Parasitol Res. 2015 Jul;114(7):2629-37. doi: 10.1007/s00436-015-4467-2. Epub 2015 Apr 23. PubMed PMID: 25903007.

4: Piner P, Üner N. Neurotoxic effects of lambda-cyhalothrin modulated by piperonyl butoxide in the brain of Oreochromis niloticus. Environ Toxicol. 2014 Nov;29(11):1275-82. doi: 10.1002/tox.21858. Epub 2013 Mar 5. PubMed PMID: 23460558.

5: Abbas N, Khan HA, Shad SA. Resistance of the house fly Musca domestica (Diptera: Muscidae) to lambda-cyhalothrin: mode of inheritance, realized heritability, and cross-resistance to other insecticides. Ecotoxicology. 2014 Jul;23(5):791-801. doi: 10.1007/s10646-014-1217-7. Epub 2014 Mar 8. PubMed PMID: 24609299.

6: Liu J, Yang X, Zhang Y. Characterization of a lambda-cyhalothrin metabolizing glutathione S-transferase CpGSTd1 from Cydia pomonella (L.). Appl Microbiol Biotechnol. 2014 Nov;98(21):8947-62. doi: 10.1007/s00253-014-5786-4. Epub 2014 May 15. PubMed PMID: 24827500.

7: Arouri R, Le Goff G, Hemden H, Navarro-Llopis V, M'saad M, Castañera P, Feyereisen R, Hernández-Crespo P, Ortego F. Resistance to lambda-cyhalothrin in Spanish field populations of Ceratitis capitata and metabolic resistance mediated by P450 in a resistant strain. Pest Manag Sci. 2015 Sep;71(9):1281-91. doi: 10.1002/ps.3924. Epub 2014 Dec 4. PubMed PMID: 25296621.

8: Mutagahywa J, Ijumba JN, Pratap HB, Molteni F, Mugarula FE, Magesa SM, Ramsan MM, Kafuko JM, Nyanza EC, Mwaipape O, Rutta JG, Mwalimu CD, Ndong I, Reithinger R, Thawer NG, Ngondi JM. The impact of different sprayable surfaces on the effectiveness of indoor residual spraying using a micro encapsulated formulation of lambda-cyhalothrin against Anopheles gambiae s.s. Parasit Vectors. 2015 Apr 3;8:203. doi: 10.1186/s13071-015-0795-4. PubMed PMID: 25890339; PubMed Central PMCID: PMC4392635.

9: Wu J, Smith MT. Lethal Effects of Lambda-Cyhalothrin and its Commercial Formulation on Asian Longhorned Beetle (Coleoptera: Cerambycidae): Implications for Population Suppression, Tree Protection, Eradication, and Containment. J Econ Entomol. 2015 Feb;108(1):150-6. doi: 10.1093/jee/tou052. Epub 2015 Feb 4. PubMed PMID: 26470115.

10: Rodrigues AR, Siqueira HA, Torres JB. Enzymes mediating resistance to lambda-cyhalothrin in Eriopis connexa (Coleoptera: Coccinellidae). Pestic Biochem Physiol. 2014 Mar;110:36-43. doi: 10.1016/j.pestbp.2014.02.005. Epub 2014 Mar 5. PubMed PMID: 24759049.

11: Gupta K, Baruah PP. Effect of lambda cyhalothrin on Calothrix sp. (GUEco 1001), an autochthonous cyanobacterium of rice fields of Brahmaputra floodplain. Environ Sci Pollut Res Int. 2015 Dec;22(23):18554-60. doi: 10.1007/s11356-015-5181-4. Epub 2015 Sep 17. PubMed PMID: 26377968.

12: Xi J, Pan Y, Bi R, Gao X, Chen X, Peng T, Zhang M, Zhang H, Hu X, Shang Q. Elevated expression of esterase and cytochrome P450 are related with lambda-cyhalothrin resistance and lead to cross resistance in Aphis glycines Matsumura. Pestic Biochem Physiol. 2015 Feb;118:77-81. doi: 10.1016/j.pestbp.2014.12.002. Epub 2014 Dec 9. PubMed PMID: 25752434.

13: Muzari OM, Adamczyk R, Davis J, Ritchie S, Devine G. Residual effectiveness of lambda-cyhalothrin harbourage sprays against foliage-resting mosquitoes in north Queensland. J Med Entomol. 2014 Mar;51(2):444-9. PubMed PMID: 24724295.

14: Colombo R, Ferreira TC, Alves SA, Carneiro RL, Lanza MR. Application of the response surface and desirability design to the Lambda-cyhalothrin degradation using photo-Fenton reaction. J Environ Manage. 2013 Mar 30;118:32-9. doi: 10.1016/j.jenvman.2012.12.035. Epub 2013 Feb 1. PubMed PMID: 23380363.

15: Torres JB, Rodrigues AR, Barros EM, Santos DS. Lambda-Cyhalothrin Resistance in the Lady Beetle Eriopis connexa (Coleoptera: Coccinellidae) Confers Tolerance to Other Pyrethroids. J Econ Entomol. 2015 Feb;108(1):60-8. doi: 10.1093/jee/tou035. Epub 2015 Jan 24. PubMed PMID: 26470104.

16: Rodrigues AR, Spindola AF, Torres JB, Siqueira HA, Colares F. Response of different populations of seven lady beetle species to lambda-cyhalothrin with record of resistance. Ecotoxicol Environ Saf. 2013 Oct;96:53-60. doi: 10.1016/j.ecoenv.2013.06.014. Epub 2013 Jul 12. PubMed PMID: 23856123.

17: George T, Beevi SN, Xavier G, Kumar NP, George J. Dissipation kinetics and assessment of processing factor for chlorpyrifos and lambda-cyhalothrin in cardamom. Environ Monit Assess. 2013 Jun;185(6):5277-84. doi: 10.1007/s10661-012-2943-z. Epub 2012 Oct 19. PubMed PMID: 23079795.

18: Cui B, Feng L, Pan Z, Yu M, Zeng Z, Sun C, Zhao X, Wang Y, Cui H. Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin. PLoS One. 2015 Aug 17;10(8):e0135953. doi: 10.1371/journal.pone.0135953. eCollection 2015. PubMed PMID: 26281043; PubMed Central PMCID: PMC4539193.

19: Fan S, Zhang F, Deng K, Yu C, Liu S, Zhao P, Pan C. Spinach or amaranth contains highest residue of metalaxyl, fluazifop-P-butyl, chlorpyrifos, and lambda-cyhalothrin on six leaf vegetables upon open field application. J Agric Food Chem. 2013 Mar 6;61(9):2039-44. doi: 10.1021/jf304710u. Epub 2013 Feb 22. PubMed PMID: 23387923.

20: Fetoui H, Feki A, Salah GB, Kamoun H, Fakhfakh F, Gdoura R. Exposure to lambda-cyhalothrin, a synthetic pyrethroid, increases reactive oxygen species production and induces genotoxicity in rat peripheral blood. Toxicol Ind Health. 2015 May;31(5):433-41. doi: 10.1177/0748233713475516. Epub 2013 Feb 13. PubMed PMID: 23406951.