A 71497

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571184

CAS#: 134762-03-1

Description: A 71497 is the 3-formyl derivative of the antibiotic tosufloxacin. It produces high plasma levels of tosufloxacin to improve solubility of the drug for the environment of the human body.

Chemical Structure

A 71497
CAS# 134762-03-1

Theoretical Analysis

MedKoo Cat#: 571184
Name: A 71497
CAS#: 134762-03-1
Chemical Formula: C19H16ClF3N4O2
Exact Mass: 424.0914
Molecular Weight: 424.81
Elemental Analysis: C, 53.72; H, 3.80; Cl, 8.34; F, 13.42; N, 13.19; O, 7.53

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Pricing updated 2021-03-05. Prices are subject to change without notice.

A 71497 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Synonym: A 71497; A-71497; A71497

IUPAC/Chemical Name: 1,8-Naphthyridine-3-carboxaldehyde, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, monohydrochloride


InChi Code: InChI=1S/C19H15F3N4O2.ClH/c20-11-1-2-16(14(21)5-11)26-7-10(9-27)17(28)13-6-15(22)19(24-18(13)26)25-4-3-12(23)8-25;/h1-2,5-7,9,12H,3-4,8,23H2;1H

SMILES Code: O=CC1=CN(C2=CC=C(F)C=C2F)C3=NC(N4CC(N)CC4)=C(F)C=C3C1=O.[H]Cl

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Handling Instructions:

Preparing Stock Solutions

The following data is based on the product molecular weight 424.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Chu DT, Lico IM, Swanson RN, Marsh KC, Plattner JJ, Pernet AG. Synthesis and biological properties of A-71497: a prodrug of tosufloxacin. Drugs Exp Clin Res. 1990;16(9):435-43. PubMed PMID: 2100244.