NCGC607
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MedKoo CAT#: 561296

CAS#: 1462267-07-7

Description: NCGC607 is a a small-molecule noninhibitory chaperone of glucocerebrosidase.


Price and Availability

Size Price Shipping out time Quantity
5mg USD 330 2 Weeks
10mg USD 570 2 Weeks
25mg USD 1200 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-08-03. Prices are subject to change without notice.

NCGC607, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 561296
Name: NCGC607
CAS#: 1462267-07-7
Chemical Formula: C24H22IN3O4
Exact Mass: 543.0655
Molecular Weight: 543.36
Elemental Analysis: C, 53.05; H, 4.08; I, 23.36; N, 7.73; O, 11.78


Synonym: NCGC607; NCGC 607; NCGC-607; NCGC00241607;

IUPAC/Chemical Name: 2-[2-(4-Iodoanilino)-2-oxoethoxy]-N-[2-(N-methylanilino)-2-oxoethyl]benzamide

InChi Key: HFVDMJQQAKLUSN-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H22IN3O4/c1-28(19-7-3-2-4-8-19)23(30)15-26-24(31)20-9-5-6-10-21(20)32-16-22(29)27-18-13-11-17(25)12-14-18/h2-14H,15-16H2,1H3,(H,26,31)(H,27,29)

SMILES Code: O=C(NCC(N(C)C1=CC=CC=C1)=O)C2=CC=CC=C2OCC(NC3=CC=C(I)C=C3)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Aflaki E, Borger DK, Moaven N, Stubblefield BK, Rogers SA, Patnaik S, Schoenen FJ, Westbroek W, Zheng W, Sullivan P, Fujiwara H, Sidhu R, Khaliq ZM, Lopez GJ, Goldstein DS, Ory DS, Marugan J, Sidransky E. A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism. J Neurosci. 2016 Jul 13;36(28):7441-52. doi: 10.1523/JNEUROSCI.0636-16.2016. PubMed PMID: 27413154; PubMed Central PMCID: PMC4945664.