A 274

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571095

CAS#: 77273-75-7

Description: A 274 is a highly aromatic, monosubstituted phenol antioxidant generated during differentiation of neuroblastoma cells. It is extensively conjugated and present as a common trace constituent in randomly selected batches of commercial tissue culture media.


Price and Availability

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A 274 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 571095
Name: A 274
CAS#: 77273-75-7
Chemical Formula: C19H14O2
Exact Mass: 274.0994
Molecular Weight: 274.32
Elemental Analysis: C, 83.19; H, 5.14; O, 11.66


Synonym: A 274; A274; A-274

IUPAC/Chemical Name: 4-(9H-xanthen-9-yl)phenol

InChi Key: OIXOSCRCPTVMFN-UHFFFAOYSA-N

InChi Code: 1S/C19H14O2/c20-14-11-9-13(10-12-14)19-15-5-1-3-7-17(15)21-18-8-4-2-6-16(18)19/h1-12,19-20H

SMILES Code: OC(C=C1)=CC=C1C2C3=CC=CC=C3OC4=CC=CC=C24


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Arneson RM, Hinds JL, Wander JD. Antioxidants in neoplastic cells: IV. Evidence that the phenolic antioxidant A274 is 9-(4-hydroxyphenyl)xanthene, an artifact in tissue culture media. Lipids. 1981 Jan;16(1):82-6. doi: 10.1007/BF02534929. PubMed PMID: 27521021.