WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 571019
Description: A 121 is a non-polyene antifungal antibiotic, produced by an unidentified strain of Streptomyces. It is active against a number of filamentous fungi including some plant and human pathogens. The presence of an alpha-ketol system in the molecule is required for A 121 to exhibit antibiotic properties.
MedKoo Cat#: 571019
Name: A 121
Chemical Formula: C18H30O5
Exact Mass: 326.2093
Molecular Weight: 326.43
Elemental Analysis: C, 66.23; H, 9.26; O, 24.51
This product is not in stock, which may be available by custom synthesis.
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Synonym: A 121
IUPAC/Chemical Name: 1-(2,3-dimethyl-2-(2-methylbut-3-en-2-yl)-2,3-dihydrofuran-3-yl)-3,5-dihydroxy-4-methoxyhexan-2-one
InChi Key: BSIAHHIPMGVHJM-UHFFFAOYSA-N
InChi Code: 1S/C18H30O5/c1-8-16(3,4)18(6)17(5,9-10-23-18)11-13(20)14(21)15(22-7)12(2)19/h8-10,12,14-15,19,21H,1,11H2,2-7H3
SMILES Code: CC(C(C(C(=O)CC1(C=COC1(C)C(C)(C)C=C)C)O)OC)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 326.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Singh S, Samanta TB. A121--an antifungal compound from Streptomyces species. Microbios. 1992;71(288-289):217-24. PubMed PMID: 1479922.
2: Singh SK, Samanta TB. A121--a new antifungal antibiotic. Indian J Exp Biol. 1978 Jun;16(6):708-10. PubMed PMID: 700804.