A 121

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571019

CAS#: 68072-84-4

Description: A 121 is a non-polyene antifungal antibiotic, produced by an unidentified strain of Streptomyces. It is active against a number of filamentous fungi including some plant and human pathogens. The presence of an alpha-ketol system in the molecule is required for A 121 to exhibit antibiotic properties.


Chemical Structure

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A 121
CAS# 68072-84-4

Theoretical Analysis

MedKoo Cat#: 571019
Name: A 121
CAS#: 68072-84-4
Chemical Formula: C18H30O5
Exact Mass: 326.2093
Molecular Weight: 326.43
Elemental Analysis: C, 66.23; H, 9.26; O, 24.51

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: A 121

IUPAC/Chemical Name: 1-(2,3-dimethyl-2-(2-methylbut-3-en-2-yl)-2,3-dihydrofuran-3-yl)-3,5-dihydroxy-4-methoxyhexan-2-one

InChi Key: BSIAHHIPMGVHJM-UHFFFAOYSA-N

InChi Code: 1S/C18H30O5/c1-8-16(3,4)18(6)17(5,9-10-23-18)11-13(20)14(21)15(22-7)12(2)19/h8-10,12,14-15,19,21H,1,11H2,2-7H3

SMILES Code: CC(C(C(C(=O)CC1(C=COC1(C)C(C)(C)C=C)C)O)OC)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 326.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Singh S, Samanta TB. A121--an antifungal compound from Streptomyces species. Microbios. 1992;71(288-289):217-24. PubMed PMID: 1479922.

2: Singh SK, Samanta TB. A121--a new antifungal antibiotic. Indian J Exp Biol. 1978 Jun;16(6):708-10. PubMed PMID: 700804.