WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 561234
CAS#: 870762-83-7
Description: CYM-5478 is a potent, selective agonist for S1P2. Under nutrient-deprivation stress produced by serum-starvation, CYM-5478 induced a statistically significant increase in the viability of C6 cells in a dose dependent manner at concentrations above 100 nM.
MedKoo Cat#: 561234
Name: CYM-5478
CAS#: 870762-83-7
Chemical Formula: C21H19F3N2O2
Exact Mass: 388.1399
Molecular Weight: 388.4
Elemental Analysis: C, 64.94; H, 4.93; F, 14.67; N, 7.21; O, 8.24
Synonym: CYM-5478; CYM 5478; CYM5478
IUPAC/Chemical Name: 1-[2-(1-Benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]-5-(trifluoromethyl)pyridin-2-one
InChi Key: RGSGTUIDJXHTTO-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H19F3N2O2/c1-14-10-18(15(2)26(14)11-16-6-4-3-5-7-16)19(27)13-25-12-17(21(22,23)24)8-9-20(25)28/h3-10,12H,11,13H2,1-2H3
SMILES Code: O=C1C=CC(C(F)(F)F)=CN1CC(C2=C(C)N(CC3=CC=CC=C3)C(C)=C2)=O
1: Deron R. Herr, Marie J. Y. Reolo, Yee Xin Peh, Wei Wang, Chang-Wook Lee, Rich Rivera, Ian C. Paterson & Jerold Chun. Sphingosine 1-phosphate receptor 2 (S1P2) attenuates reactive oxygen species formation and inhibits cell death: implications for otoprotective therapy. Scientific Reports 6, Article number: 24541 (2016) doi:10.1038/srep24541.