NTRC-844

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MedKoo CAT#: 561220

CAS#: 1811503-67-9

Description: NTRC-844 is a selective antagonist for the rat neurotensin receptor type 2 (NTS2).


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-08-03. Prices are subject to change without notice.

NTRC-844 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 561220
Name: NTRC-844
CAS#: 1811503-67-9
Chemical Formula: C28H28FN3O4
Exact Mass: 489.2064
Molecular Weight: 489.55
Elemental Analysis: C, 68.70; H, 5.77; F, 3.88; N, 8.58; O, 13.07


Synonym: NTRC-844; NTRC844; NTRC 844

IUPAC/Chemical Name: 2-(1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazole-3-carboxamido)adamantane-2-carboxylic acid

InChi Key: CFHHPKGFMMIMOJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C28H28FN3O4/c1-36-25-5-3-2-4-22(25)24-15-23(31-32(24)21-8-6-20(29)7-9-21)26(33)30-28(27(34)35)18-11-16-10-17(13-18)14-19(28)12-16/h2-9,15-19H,10-14H2,1H3,(H,30,33)(H,34,35)

SMILES Code: O=C(C1(NC(C2=NN(C3=CC=C(F)C=C3)C(C4=CC=CC=C4OC)=C2)=O)C(C5)CC6CC5CC1C6)O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Thomas JB, Vivancos M, Giddings AM, Wiethe RW, Warner KR, Murza A, Besserer-Offroy É, Longpré JM, Runyon SP, Decker AM, Gilmour BP, Sarret P. Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a Selective Antagonist for the Rat Neurotensin Receptor Type 2. ACS Chem Neurosci. 2016 Sep 21;7(9):1225-31.doi: 10.1021/acschemneuro.6b00097. Epub 2016 Jul 13. PubMed PMID: 27359371.