MDK-6303

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561140

CAS#: 420126-30-3

Description: MDK-6303, also known as Antitumor Compound 1, is a potent antitumor agent. The last four digits of MDK-6303's CAS registry number are used in its name.

Chemical Structure

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MDK-6303
CAS# 420126-30-3
Instruction

Theoretical Analysis

MedKoo Cat#: 561140
Name: MDK-6303
CAS#: 420126-30-3
Chemical Formula: C18H10F6N4S
Exact Mass: 428.05
Molecular Weight: 428.356
Elemental Analysis: C, 50.47; H, 2.35; F, 26.61; N, 13.08; S, 7.48

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: MDK-6303; MDK 6303; MDK6303; Antitumor Compound 1

IUPAC/Chemical Name: [4-(2-Trifluoromethyl-imidazo[1,2-a]pyridin-3-yl)-thiazol-2-yl]-(4-trifluoromethyl-phenyl)-amine

InChi Key: KYPPJHVEENIEGO-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H10F6N4S/c19-17(20,21)10-4-6-11(7-5-10)25-16-26-12(9-29-16)14-15(18(22,23)24)27-13-3-1-2-8-28(13)14/h1-9H,(H,25,26)

SMILES Code: FC(C1=CC=C(NC2=NC(C3=C(C(F)(F)F)N=C4C=CC=CN43)=CS2)C=C1)(F)F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 428.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Kasuya, Hiroshi; Miyazaki, Hideki; Hayakawa, Ichio; Kanno, Yuichi; Watanabe, Kazuyoshi Kokai Tokkyo Koho. Polymer-linked imidazopyridines useful as tumor-targeting cytotoxic agents. (2004), JP 2004002826 A 20040108.

2: Hayakawa, Ichio; Kanno, Yuichi; Azuma, Toshiki; Furukawa, Hidehiko; Naruto, Shunji; Kurakata, Shinichi From Jpn. Kokai Tokkyo Koho. Pharmaceuticals containing imidazopyridines for prophylactic and therapeutic treatment of tumor. (2003), JP 2003313126A 20031106.

3: Hayakawa, Ichiro; Sugano, Yuichi; Agatsuma, Toshinori; Furukawa, Hidehiko; Kurakata, Shinichi; Naruto, Shunji. Preparation of imidazopyridine derivatives as antitumor agents. From PCT Int. Appl. (2002), WO 2002034748 A1 20020502.