Ifenprodil hemitartrate
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 329680

CAS#: 23210-58-4 (tartrate)

Description: Ifenprodil is an inhibitor of the NMDA receptor, specifically of GluN1 (glycine-binding NMDA receptor subunit 1) and GluN2B (glutamate-binding NMDA receptor subunit 2) subunits. Additionally, ifenprodil inhibits GIRK channels, and interacts with alpha1 adrenergic, serotonin, and sigma receptors.


Chemical Structure

img
Ifenprodil hemitartrate
CAS# 23210-58-4 (tartrate)

Theoretical Analysis

MedKoo Cat#: 329680
Name: Ifenprodil hemitartrate
CAS#: 23210-58-4 (tartrate)
Chemical Formula: C46H60N2O10
Exact Mass:
Molecular Weight: 800.99
Elemental Analysis: C, 68.98; H, 7.55; N, 3.50; O, 19.97

Price and Availability

Size Price Availability Quantity
10.0mg USD 150.0 2 Weeks
20.0mg USD 250.0 2 Weeks
50.0mg USD 450.0 2 Weeks
Bulk inquiry

Related CAS #: 23210-58-4 (tartrate)   23210-56-2 (free base)   66157-43-5 (tartrate)    

Synonym: Ifenprodil; Ifenprodil hemitartrate; Ifenprodil tartrate; RC 61-91; RC-61-91; RC61-91; RC 6191; RC61-91; RC6191;

IUPAC/Chemical Name: 4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phenol; (2R,3R)-2,3-dihydroxysuccinate (2:1)

InChi Key: DMPRDSPPYMZQBT-CEAXSRTFSA-N

InChi Code: InChI=1S/2C21H27NO2.C4H6O6/c2*1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17;5-1(3(7)8)2(6)4(9)10/h2*2-10,16,18,21,23-24H,11-15H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1

SMILES Code: OC1=CC=C(C(O)C(N2CCC(CC3=CC=CC=C3)CC2)C)C=C1.OC4=CC=C(C(O)C(N5CCC(CC6=CC=CC=C6)CC5)C)C=C4.O=C(O)[C@H](O)[C@@H](O)C(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 800.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x


Additional Information

NMDA receptors are multimeric ionotropic glutamate receptors composed of four subunits. GluN1 is obligate for functional expression. Other subunits include GluN2A, GluN2B, and the more recently discovered GluN3 subunits. Ifenprodil selectively blocks NMDA receptors containing the GluN2B subunit.