WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 551027
Description: YKAs3003 is a novel potent inhibitor of pathogenic KAS III. This antimicrobial compound displays minimal inhibitory concentration (MIC) values in the range 128-256 microg/mL against various bacteria.
MedKoo Cat#: 551027
Chemical Formula: C13H17NO2
Exact Mass: 219.1259
Molecular Weight: 219.284
Elemental Analysis: C, 71.21; H, 7.81; N, 6.39; O, 14.59
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: YKAs3003; YKAs-3003; YKAs3003
IUPAC/Chemical Name: 4-Cyclohexyliminomethyl-benzene-1,3-diol
InChi Key: UGMBMYJAUTUEJB-NTEUORMPSA-N
InChi Code: InChI=1S/C13H17NO2/c15-12-7-6-10(13(16)8-12)9-14-11-4-2-1-3-5-11/h6-9,11,15-16H,1-5H2/b14-9+
SMILES Code: OC1=CC=C(/C=N/C2CCCCC2)C(O)=C1
Appearance: White to off-white solid powder.
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 219.284 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Lee JY, Jeong KW, Shin S, Lee JU, Kim Y. Discovery of novel selective inhibitors of Staphylococcus aureus β-ketoacyl acyl carrier protein synthase III. Eur J Med Chem. 2012 Jan;47(1):261-9. doi: 10.1016/j.ejmech.2011.10.052. Epub 2011 Nov 4. PubMed PMID: 22104972.
2: Lee JY, Jeong KW, Lee JU, Kang DI, Kim Y. Novel E. coli beta-ketoacyl-acyl carrier protein synthase III inhibitors as targeted antibiotics. Bioorg Med Chem. 2009 Feb 15;17(4):1506-13. doi: 10.1016/j.bmc.2009.01.004. Epub 2009 Jan 11. PubMed PMID: 19185501.