WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526402

CAS#: 125464-42-8

Description: Saclofen is a selective antagonist of GABAB receptors.

Chemical Structure

CAS# 125464-42-8

Theoretical Analysis

MedKoo Cat#: 526402
Name: Saclofen
CAS#: 125464-42-8
Chemical Formula: C9H12ClNO3S
Exact Mass: 249.0226
Molecular Weight: 249.709
Elemental Analysis: C, 43.29; H, 4.84; Cl, 14.20; N, 5.61; O, 19.22; S, 12.84

Price and Availability

Size Price Availability Quantity
5.0mg USD 190.0 2 Weeks
10.0mg USD 350.0 2 Weeks
20.0mg USD 550.0 2 Weeks
50.0mg USD 1150.0 2 Weeks
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Synonym: Saclofen

IUPAC/Chemical Name: 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid


InChi Code: InChI=1S/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14)

SMILES Code: O=S(CC(C1=CC=C(Cl)C=C1)CN)(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 249.709 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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20: Varani AP, Balerio GN. GABA(B) receptors involvement in the effects induced by nicotine on anxiety-related behaviour in mice. Pharmacol Res. 2012 May;65(5):507-13. doi: 10.1016/j.phrs.2012.03.001. Epub 2012 Mar 13. PubMed PMID: 22430317.