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MedKoo CAT#: 526400

CAS#: 342595-74-8

Description: UMK57 is a novel inhibitor of chromosomal instability, potentiating MCAK in vivo and transiently suppressing chromosome mis-segregation in CIN cancer cells.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-10-29. Prices are subject to change without notice.

UMK57 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 526400
Name: UMK57
CAS#: 342595-74-8
Chemical Formula: C17H17N3S
Exact Mass: 295.1143
Molecular Weight: 295.404
Elemental Analysis: C, 69.12; H, 5.80; N, 14.22; S, 10.85

Synonym: UMK57, UMK-57, UMK 57

IUPAC/Chemical Name: 4-Pyrrolidin-1-yl-5-p-tolyl-thieno[2,3-d]pyrimidine


InChi Code: InChI=1S/C17H17N3S/c1-12-4-6-13(7-5-12)14-10-21-17-15(14)16(18-11-19-17)20-8-2-3-9-20/h4-7,10-11H,2-3,8-9H2,1H3


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Orr B, Talje L, Liu Z, Kwok BH, Compton DA. Adaptive Resistance to an Inhibitor of Chromosomal Instability in Human Cancer Cells. Cell Rep. 2016 Nov 8;17(7):1755-1763. doi: 10.1016/j.celrep.2016.10.030. PubMed PMID: 27829147; PubMed Central PMCID: PMC5130158.