WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 407495
CAS#: 140651-18-9
Description: CAY10574, also known as Cdk9 Inhibitor II, is a potent, selective inhibitor of Cdk9 in vitro with an IC50 value of 0.35 µM. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 µM, respectively.
MedKoo Cat#: 407495
Name: CAY10574
CAS#: 140651-18-9
Chemical Formula: C9H10N6O
Exact Mass: 218.0916
Molecular Weight: 218.22
Elemental Analysis: C, 49.54; H, 4.62; N, 38.51; O, 7.33
Synonym: CAY10574; CAY-10574; CAY 10574; Cdk9 Inhibitor II
IUPAC/Chemical Name: 4-[(3,5-diamino-1H-pyrazol-4-yl)azo]-phenol
InChi Key: AYZRKFOEZQBUEA-OUKQBFOZSA-N
InChi Code: InChI=1S/C9H10N6O/c10-8-7(9(11)15-14-8)13-12-5-1-3-6(16)4-2-5/h1-4,16H,(H5,10,11,14,15)/b13-12+
SMILES Code: OC1=CC=C(/N=N/C2=C(N)NN=C2N)C=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 218.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
