WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 530653
Description: L-573655 is an antibacterial agents that target lipid A biosynthesis in gram-negative bacteria.
MedKoo Cat#: 530653
Chemical Formula: C10H10N2O3
Exact Mass: 206.0691
Molecular Weight: 206.201
Elemental Analysis: C, 58.25; H, 4.89; N, 13.59; O, 23.28
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: L-573655; L 573655; L573655; L-573,655; L 573,655; L573,655;
IUPAC/Chemical Name: N-hydroxy-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxamide
InChi Key: WXOVMEKLQFRMEM-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H10N2O3/c13-9(12-14)8-6-15-10(11-8)7-4-2-1-3-5-7/h1-5,8,14H,6H2,(H,12,13)
SMILES Code: O=C(C1N=C(C2=CC=CC=C2)OC1)NO
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 206.201 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Jackman JE, Fierke CA, Tumey LN, Pirrung M, Uchiyama T, Tahir SH, Hindsgaul O,
Raetz CR. Antibacterial agents that target lipid A biosynthesis in gram-negative
bacteria. Inhibition of diverse
UDP-3-O-(r-3-hydroxymyristoyl)-n-acetylglucosamine deacetylases by substrate
analogs containing zinc binding motifs. J Biol Chem. 2000 Apr 14;275(15):11002-9.
PubMed PMID: 10753902.
2: Chen MH, Steiner MG, de Laszlo SE, Patchett AA, Anderson MS, Hyland SA, Onishi
HR, Silver LL, Raetz CR. Carbohydroxamido-oxazolidines: antibacterial agents that
target lipid A biosynthesis. Bioorg Med Chem Lett. 1999 Feb 8;9(3):313-8. PubMed
3: Onishi HR, Pelak BA, Gerckens LS, Silver LL, Kahan FM, Chen MH, Patchett AA,
Galloway SM, Hyland SA, Anderson MS, Raetz CR. Antibacterial agents that inhibit
lipid A biosynthesis. Science. 1996 Nov 8;274(5289):980-2. PubMed PMID: 8875939.